Targeting energy pathways in kidney disease: the roles of sirtuins, AMPK, and PGC1 alphaacute kidney injurydiabetic nephropathyfibrosismitochondriaproteinuriaThe kidney has extraordinary metabolic demands to sustain the active transport of solutes that is critical to renal filtration and clearance. ...
NAD+, decreased ADP and AMP contents and the ratio of AMP/ATP, reduced the level of ROS and MDA, enhanced SOD activity, evidently increased the levels of AMPK, SIRT1 and PGC-1 alpha mRNA, up-regulated the expressions of AMPK, pAMPK, SIRT1, PGC-1alpha, NRF1, TFAM and FOXO1 proteins...
Faculty Opinions recommendation of Fibroblast growth factor 21 regulates energy metabolism by activating the AMPK-SIRT1-PGC-1alpha pathway. 来自 Semantic Scholar 喜欢 0 阅读量: 1 作者:P Griffin,N Kumar DOI: 10.3410/f.4113957.3893055 年份: 2010 ...
The objective of this study is to examine the impact of resveratrol on the activation of the AMP-activated protein kinase/peroxisome proliferator gamma receptor coactivator 1-alpha mechanism of signal pathway on colorectal cancer. Set up blank control group,...
Furthermore, our result demonstrated that nanocurcumin treatment combined with exercise increased the phosphorylation of AMPK and PGC-1伪. Addition, nanocurcumin treatment alone, without exercise, also increased PGC-1伪 protein expression. This current result suggests that nanocurcumin coul...
(2009) Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1alpha in skeletal muscle . Aging (Albany NY) 1 : 771–783Palacios OM , Carmona JJ , Michan S , Chen KY , Manabe Y , Ward JL 3rd , Goodyear LJ , Tong Q ( 2009 ) Diet and exercise ...
AMPK/PGC-1 alphaSignal pathViralThis study was to investigate the secretion of related factors by alveolar macrophages and AMPK/PGC-1 alpha signal pathway in viral acute lung injury (VALI) patients. 30 SD rats were randomly divided into blank control group (BCG) and VALI group (VALIG) with...
C. L. Zhang, H. Feng, L. Li et al., "Globular CTRP3 pro- motes mitochondrial biogenesis in cardiomyocytes through AMPK/PGC-1alpha pathway," Biochimica et Biophysica Acta (BBA) - General Subjects, vol. 1861, no. 1, Part A, pp. 3085-3094, 2017....
Zhang CL, Feng H, Li L, Wang JY, Wu D, Hao YT, Wang Z, Zhang Y and Wu LL. Globular CTRP3 promotes mitochondrial biogenesis in cardio- myocytes through AMPK/PGC-1alpha pathway. Biochim Biophys Acta 2016; 1861: 3085- 3094.C.-L. Zhang, H. Feng, L. Li, J.-Y. Wang, D. Wu,...
Punicalagin Activates AMPK/PGC-1 alpha/Nrf2 Cascade in Mice: The Potential Protective Effect against Prenatal StressAMP-activated protein kinasemitochondrial biogenesisNrf2 pathwayprenatal stresspunicalaginScope Prenatal stress is closely associated with poor health outcomes for offspring, yet the specific ...