Side-effects of aminopenicillin therapy are reviewed on the basis of nine comparative studies of ampicillin and bacampicillin, and available literature data from investigations with talampicillin, pivampicillin, bacampicillin and amoxycillin. Diarrhoea is more common with ampicillin than with newer aminope...
Three quercetin derivatives with enhanced radical-scavenging activity were designed and synthesised. Because the radical-scavenging reaction of quercetin is known to proceed via an electron transfer from quercetin to radicals, producing the corresponding quercetin radical cation intermediate, the introduction ...
In 1976, cys was first used for the treatment ofcystinosis, approved by the US Food and Drug Administration (FDA), and commercialized in the 1990s [6]. Till now, cys is the only specific targeted therapy available for patients with cystinosis. The latter is a rare autosomal recessivemetab...
select an AED with a tolerable side effect and toxicity profile; and slowly titrate the selected AED to the desired dose, analyzing the patient’s response to treatment. In some refractory patients, presenting neurotoxic adverse effects with high-dose monotherapy, polytherapy with lower or moderate...
In addition to meeting protein needs, the administration rate should be governed, especially during the first few day of therapy, by the patient’s tolerance to dextrose. Daily intake of amino acids and dextrose should be increased gradually to the maximum required dose as indicated by frequent ...
In patients with localized , radical prostatectomy and radiation therapy, although effective in controlling , are often associated with significant side effects attributable to injury of adjacent tissues. Moreover, patients with eventual... SF Shariat,S Desai,W Song,... - 《Cancer Research》 被引...
Because of its central role in methylation, Met is considered a candidate target for tumor therapy driven by ten-eleven translocation (TET), isocitrate dehydrogenase (IDH) proteins, methyltransferases, and other phenotypic modifiers. Anti-tumor effects of the Met-free diet were first reported in Wal...
Anti-aging therapy Taurine is a nutrient found in certain foods, such as fish, shellfish, chicken, turkey and beef. It is also naturally produced in some tissues of the human body, especially the liver, and is important to the functioning of the central nervous system, immunity, eyesight an...
These side effects may be minimized by the use of compounds known to have a protective effect on normal ocular tissues without impeding the benefits of therapy. Phosphorothioates, first developed under the Antiradiation Drug Development Program of the U.S. Army Medical Research and Development ...
Glatiramer acetate (Copaxone®) therapy for multiple sclerosis Suhayl Dhib-Jalbut, in Pharmacology & Therapeutics, 2003 GA is a synthetic mixture of four amino acid copolymers; namely, l-alanine, l-lysine, l-glutamic acid, and l-tyrosine in a molar ratio of 4.2, 3.4, 1.1, and 1.0. W...