必应词典为您提供aminoterminus的释义,网络释义: 氨基端;胺基端;
Previous studies of the rat follicle-stimulating hormone receptor (rFSHR) demonstrated that the amino terminus is important in FSH binding and signal transduction. To define the structure–function correlates of this region, we prepared deletion and alanine scanning mutants of amino acids (a.a.) 9...
In the present studies, two naturally occurring cystic fibrosis mutations in the amino terminus of CFTR, R31C, and R31L were examined. To determine the defect that these mutations cause, the Arg-31 mutants were expressed in COS-7 cells and their biogenesis and trafficking to the cell surface...
J. (1997) Truncation of the amino terminus of human apolipoprotein A-I substantially alters only the lipid-free conformation. Biochemistry 36, 288-300... Rogers,Danise,P.,... - 《Biochemistry》 被引量: 101发表: 1997年 Structural basis for distinct functions of the naturally occurring Cys mu...
Creating a mutation in the N-terminus of the VACV-E3L protein generates an oncolytic VACV that depends on dysregulated anti-viral signaling pathways for replication allowing for direct targeting of the cancerous cells. VACV-E3Ldel54N selectively replicates in numerous cancer cells lines and not ...
These results provide evidence that DNA binding by the evolutionarily conserved amino terminus of Rad52 is needed for the capture of the second DNA end during homologous recombination.Previous article in issue Next article in issue Sorry, something went wrong. Please try again and make sure cookies...
4 Our studies show that the binding of pol δ to PCNA is mediated by a region of peptide sequence within the 21-residue peptide in the amino terminus of pol δ region. The N2 region can be characterized by the consensus GX4GX8GX3YFY between human, Saccharomyces cerevisiae, and ...
et al. Tyrosine Sulfation of the Amino Terminus of CCR5 Facilitates HIV-1 Entry. Cell 96, 667–676 (1999). Article CAS PubMed Google Scholar Choe, H. et al. Tyrosine Sulfation of Human Antibodies Contributes to Recognition of the CCR5 Binding Region of HIV-1 gp120. Cell 114, 161–...
with high affinity to the N terminus of the MEK Ste7, and proposed that a conserved motif in Ste7, the MAPK-docking site, mediates this interaction... AJ Bardwell,LJ Flatauer,K Matsukuma,... - 《Journal of Biological Chemistry》 被引量: 366发表: 2001年 The molecular mechanism of MAPK...
The electron density maps also revealed the presence of an additional single transmembrane helix that packs against TM5, and orientated with its amino-terminus facing the cytoplasm. The maps were of sufficient quality to allow us to identify this helix as YneM, which has recently been renamed as...