The complexes of four oxime analogues of amino acids and peptides (containing {O,N} donor atoms) with Bu 2 SnO were prepared, with ligand to metal ratios of 1 : 1 or 1 : 2, by two different methods. The FT-IR and Raman spectra clearly demonstrated that the organotin(IV) moieties ...
γ-Amino acids and peptides analogues are common constituents of building blocks for numerous biologically active molecules, pharmaceuticals, and natural products. In particular, γ-amino acids are providing with better metabolic stability than α-amino acids. Herein we report a multicomponent carbonylatio...
ChemInform Abstract: AMINO ACIDS AND PEPTIDES PART 129, SYNTHESIS AND INHIBITORY PROPERTIES OF OXYTOCIN ANALOGUES MODIFIED IN THE AMINO-TERMINAL REGION OF THE MOLECULEhormonesThe memory-modulating effects of subcutaneously administered oxytocin and related peptides were investigated in the social recognition...
ChemInform Abstract: AMINO ACIDS AND PEPTIDES PART 122, SYNTHESIS AND SOME BIOLOGICAL ACTIVITIES OF ANALOGUES OF DEAMINO‐VASOPRESSIN WITH THE DISULPHIDE BRIDGE ALTERED TO A THIOETHER BRIDGEhormonesDie Desamino-vasopressin-Analogen (I) werden stufenweise nach bekannten Methoden aufgebaut.doi:10.1002/...
new roles for amino acids in physiology and pathophysiology, biology, amino acid analogues and derivatives, polyamines, radiated amino acids, peptides, stable isotopes and isotopes of amino acids. Applications in medicine, food chemistry, nutrition, gastroenterology, nephrology, neurochemistry, pharmacology...
In this study, structural topology scale (ST-scale) was recruited as a novel structural topological descriptor derived from principal component analysis on 827 structural variables of 167 amino acids. By using partial least squares (PLS), we applied ST-scale for the study of quantitative sequence-...
new roles for amino acids in physiology and pathophysiology, biology, amino acid analogues and derivatives, polyamines, radiated amino acids, peptides, stable isotopes and isotopes of amino acids. Applications in medicine, food chemistry, nutrition, gastroenterology, nephrology, neurochemistry, pharmacology...
Synthesis of tetrazole analogues of amino acids using Fmoc chemistry: isolation of amino free tetrazoles and their incorporation into peptides An efficient synthesis of tetrazole analogues of amino acids starting from Nα-Fmoc amino acid in a three-step protocol is reported. The free amino tetrazo...
Amino acid metabolism plays important roles in tumor biology and tumor therapy. Accumulating evidence has shown that amino acids contribute to tumorigenesis and tumor immunity by acting as nutrients, signaling molecules, and could also regulate gene tran
Ribosome-mediated polymerization of backbone-extended monomers into polypeptides is challenging due to their poor compatibility with the translation apparatus, which evolved to use α-L-amino acids. Moreover, mechanisms to acylate (or charge) these