amino acids, peptidesChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is ...
ChemInform Abstract: AMINO ACIDS AND PEPTIDES PART 129, SYNTHESIS AND INHIBITORY PROPERTIES OF OXYTOCIN ANALOGUES MODIFIED IN THE AMINO-TERMINAL REGION OF THE MOLECULEhormonesThe memory-modulating effects of subcutaneously administered oxytocin and related peptides were investigated in the social recognition...
In this study, structural topology scale (ST-scale) was recruited as a novel structural topological descriptor derived from principal component analysis on 827 structural variables of 167 amino acids. By using partial least squares (PLS), we applied ST-scale for the study of quantitative sequence-...
Amino acids (AAs) are one of the primary metabolic substrates for cardiac work. The correlation between AAs and both atrial fibrillation (AF) and aging has been documented. However, the relationship between AAs and age-related AF remains unclear. Methods Initially, the plasma AA levels of persis...
new roles for amino acids in physiology and pathophysiology, biology, amino acid analogues and derivatives, polyamines, radiated amino acids, peptides, stable isotopes and isotopes of amino acids. Applications in medicine, food chemistry, nutrition, gastroenterology, nephrology, neurochemistry, pharmacology...
A series of cyclic peptides, [(DipR)(WR)4], [(DipR)2(WR)3], [(DipR)3(WR)2], [(DipR)4(WR)], and [DipR]5, and their linear counterparts containing arginine (R) as positively charged residues and tryptophan (W) or diphenylalanine (Dip) as hydrophobic residues, were synthesized...
Oxygen-containing heterocycles as those of the nitrogen analogues are widely present in various kinds of natural products, such as carbohydrates, polyketides, peptides, and terpenoids, which show large potential of diverse pharmacological properties [16,17,18,19,20,21,22]. Nature-derived O-heterocyc...
Studies using S. cerevisiae provided key insight into the role of TOR as a signal integrator for amino acids. For example, rapamycin, an inhibitor of TOR, mimics the effect that amino acid starvation has on protein translation, cell cycle arrest, ribosome biogenesis and autophagy (Crespo and ...
δ-Peptides of the type described in this series are analogues of pyranosyl-RNAs with respect to their capability of base pairing in the Watson-Crick mode. An NMR-based conformational analysis of the title duplex at various levels of sophistication has been carried out: at the level of qualit...
Synthesis of tetrazole analogues of amino acids: The Fmoc approach The chemistry of heterocycles has acquired immense importance in recent years. Tetrazoles represent an important class of heterocycles which exhibit a wide... KS Sarma,VV Sureshbabu,SA Naik - International Peptide Symposium in Conjunc...