The concentration in plasma of 15 fasting amino acids were measured in 14 control volunteers and 55 cancer patients. In addition, 16 patients (7 with, 9 without total parenteral nutrition [TPN] ) with metastatic sarcoma had sequential amino acid profiles measured during 6 weeks of ablative ...
Amino Acids in Critical Care and Cancer2nd Ed Bibliogr. na konci kapitoldoi:10.1080/07315724.1996.10738024FlodinNestor W.RoutledgeJournal of the American College of Nutrition
Branched-chain amino acids (BCAAs; leucine, isoleucine, and valine) are essential amino acids that must be acquired from the diet. To support sustained biomass accumulation, cancer cells require increased levels of nutrients such as amino acids. Indeed, cancer cells have increased BCAAs uptake17,...
Amino acids are thebuilding blocksthat cells need to make proteins. While healthy cells are able to make sufficient serine and glycine, cancercellsare much more dependent on getting these vital amino acids from the diet. However, the study also found that the diet was less effective in tumours...
Branched-chain amino acids (BCAAs, i.e., valine, leucine, and isoleucine) function as nitrogen donors to generate macromolecules such as nucleotides and are indispensable for human cancer cell growth. The cell-autonomous and non-autonomous roles of altered BCAA metabolism have been implicated in ...
Free Amino Acids in the Gastric Juice of Patients with Gastric Cancer of paper chromatograph, examination was made on amino acids in gastric juice in cases with gastric cancer, gastric and duodenal ulcers and other diseases... Shimizu,Fumitoshi - 《Tohoku Journal of Experimental Medicine》 被引量...
tumors may be trying to feed their own appetite for amino acids that they need to build cancerous cells. The researchers are also exploring possible links between this early protein breakdown and the wasting disease known as cachexia, which often occurs in the late stages of pancreatic cancer. ...
E. Phenylalanine and Tyrosine Answer: C 3. Glutamine amidotransferase is responsible for transferring the amide amino group to: A. Glucose molecules B. Fatty acids C. Many acceptor molecules D. Nucleotides only E. Other amino acids Answer: C ...
We show that asparagine exchanges with extracellular amino acids to regulate mTOR complex 1 (mTORC1) activation, nucleotide synthesis and proliferation. Our results indicate that glutamine contribution to cancer cell survival and proliferation is, in part, mediated by glutamine-dependent asparagine ...
and cancer. In the case of tumors, alterations in amino acid metabolism can be used not only as clinical indicators of cancer progression but also as therapeutic strategies. Since the growth and development of tumors depend on the intake of foreign amino acids, more and more studies have target...