We also used our model to predict four known protein structures with a single amino acid sequence, while many other existing methods could only obtain one possible structure for a given sequence. Conclusions The results show that our method provides a new effective and reliable tool for protein ...
Amino acid torsion angles enable prediction of protein fold classification Article Open access 10 December 2020 Machine learning approaches demonstrate that protein structures carry information about their genetic coding Article Open access 20 December 2022 Introduction The tendency to categorize and class...
Amino acid torsion angles enable prediction of protein fold classification Article Open access 10 December 2020 Impact of structure space continuity on protein fold classification Article Open access 23 March 2016 ORION: a web server for protein fold recognition and structure prediction using evolut...
In our last study we identified two unique ATP binding motifs in Class I and Class II aaRSs43, which are by now the minimal description of the two classes. Hence, a detailed study of the amino acid binding site is the logical next step to extend the picture of ligand binding in aaRSs...
The study has been extended, in a limited way, to the conformation of the ring in the amino acid proline. Since the nitrogen is tetrahedral in this (as contrasted with being planar in the prolyl residue), it is found that any one of the five atoms can be out of plane (either way)...
Despite the importance of β-strands as main building blocks in proteins, the propensity of amino acid in β-strands is not well-understood as it has been more difficult to determine experimentally compared to α-helices. Recent studies have shown that most of the amino acids have significantly...
The conformational angles were obtained using the DSSP program [32], and the difference in the backbone torsion angles, Du and Dw, for each amino acid residue was calculated. Results Sequence Conservation of E Proteins in the Flavivirus Genus Sequence conservation of E proteins among dengue ...
The conformational preferences of the 3,3-disubstituted -amino acid residue, 1-aminocyclohexaneacetic acid (3,3Ac6c) have been investigated by determining the crystal structures of the parent amino acid, the hydrochloride derivative, 10 protected derivatives and di and tripeptides. The symmetrical ...
(B) Distribution of torsion angles between the phosphate and amino acid substructure of the ligand. The orientation of the ligand in the binding site differs significantly (Mann–Whitney U \(p<0.01\)) between GluRSs and AspRSs. (C) The volume of the specificity-conferring moiety of the ...
11, No. 10, pp 763~774 (1979) X-Ray Structural Studies of Some Poly(~-amino acid)s with Hydrophobic Side Chains: Poly(L-valine), Poly(L-isoleucine), and Poly(L-phenylalanine) Osamu YAMASHITA, *1 Takashi YAMANE, *1 Tamaichi ASHIDA, *1 Shinsuke YAMASHITA,*2 and Takuya YAMASHITA*2 ...