In this chapter, the structure, function, catalytic mechanism and therapeutic application of some amino acid depriving enzymes will be reviewed. Particular attention will be given to enzymes that have potential or are currently used in the treatment of several types of cancer, namely: (1) l -...
Preparation and Characterization of Fullerene (C60)Amino Acid Nanoparticles for Liver Cancer Cell Treatment. Zhi Li,Li-li Pan,Fei-long Zhang, et al. ... Z Li,LL Pan,FL Zhang,... - 《Journal of Nanoscience & Nanotechnology》 被引量: 14发表: 2014年 Preparation and Characterization of Fuller...
including nucleotides. The key entry point is the amino acid glutamate. Glutamate and glutamine are the nitrogen donors in a wide range of biosynthetic reactions. Glutamine synthetase, which catalyzes the formation of glutamine from glutamate, is a main regulatory ...
C. IDO inhibitors for cancer treatment: lessons from ECHO-301. Semin. Immunopathol. 41, 41–48 (2019). PubMed Google Scholar Seymour, R. L., Ganapathy, V., Mellor, A. L. & Munn, D. H. A high-affinity, tryptophan-selective amino acid transport system in human macrophages. J. ...
Branched-chain amino acid (BCAA) catabolism and high levels of enzymes in the BCAA metabolic pathway have recently been shown to be associated with cancer growth and survival. However, the precise roles of BCAA metabolism in cancer growth and survival remain largely unclear. Here, we found that...
AMINO ACID-BINDED MUSTARD GAS DERIVATIVES AND THEIR USE AS AN ACTIVE SUBSTANCE IN THE TREATMENT OF TUMORS 来自 掌桥科研 喜欢 0 阅读量: 9 申请(专利)号: DE1993621729T 申请日期: 1993-07-23 公开/公告号: DE69321729T2 公开/公告日期: 1999-03-18 申请(专利权)人: CANCER RESEARCH ...
摘要: A method of administering an amino acid protocol intravenously for the treatment of a patient suffering from an autoimmune disease is provided.收藏 引用 批量引用 报错 分享 全部来源 求助全文 Google Patents 相似文献 参考文献 引证文献Essential fatty acids in the treatment and/or inhibition of ...
Zhang, Preparation and characterization of fullerene (C60) amino acid nanoparticles for liver cancer cell treatment, J Nanosci Nanotechnol. 14 (2014) 4513-4518.LI Zhi, PAN Li-li, ZHANG Fei-long, et al. Preparation and characterization of fullerene (C60) amino acid nan- oparticles for liver ...
Table 1 Drugs that target amino acid metabolism in clinical trials Full size table Asparagine has received extensive attention as a new target for cancer treatment. Knott et al. reported that the expression level of asparagine synthetase (ASNS) in breast cancer is closely related to metastatic rec...
Amino acid deprivation did not affect HPRT activity over the time course studied (Table 1). To determine if cisplatin reduced PRPP availability in other cell types, we examined human ovarian cancer cells. We found that 6 h of cisplatin treatment significantly reduced PRPP availability in IGROV-1...