AMINATION OF ALKYL HALIDESTED L. BLANEYUS3542876 1968年9月26日 1970年11月24日 Procter & Gamble Amination of alkyl halides
Direct alkylation of amines with alkyl halides is a difficult reaction to control. One alternative that works extremely well is to form theimineof an amine with an appropriate aldehyde or ketone, and then to reduce the imine to an amine. This is calledreductive aminationand avoids the problem ...
The ammonolysis process can be applied for the conversion of many raw materials such as carboxylic acids, α-olefins, alkyl halides, aldehydes, ketones and alcohols to amines [8], [9], [10], [11], among which alcohols are abundant and the ammonolysis process of alcohols with ammonia to ...
This operationally straightforward, metal-free and modular transformation forms tertiary amines, without structural constraint, via the coupling of aldehydes and secondary amines with alkyl halides. The structural and functional diversity of these readily available precursors provides a versatile and flexible ...
Palladium-catalyzed amination reactions of aryl halides have undergone rapid development in the last 12 years, largely driven by the implementation of new classes of ligands. Biaryl phosphanes have proven to provide especially active catalysts in this context. This Review discusses the application of...
W. Thaler Photo bromination of alkyl halides, an unusual orienting effect in the bromination of alkyl bromides J. Am. Chem. Soc., 85 (1963), pp. 2607-2613 CrossrefView in ScopusGoogle Scholar34 M. Ueda, A. Maeda, K. Hamaoka, M. Sasano, T. Fukuyama, I. Ryu Bromine-radical-mediated...
Direct cross-coupling of C-H bonds with Grignard reagents through cobalt catalysis. Angew. Chem. Int. Ed. 50, 1109–1113 (2011) . Article CAS Google Scholar Gao, K. & YoshikaI, N. Cobalt-catalyzed ortho-alkylation of aromatic imines with primary and secondary alkyl halides. J. Am. ...
[reaction: see text] The first direct reductive amination of mucochloric acid (1) has been accomplished. Reaction of 1 with various alkyl, aryl, and , followed by reduction in the same pot, provides an efficient method of obtaining N--3,4-dichloro-1,5-dihydro--2-one and N-aryl (or ...
University of Alberta Libraries, Information Technology Services, Piyapong Charoenwattana,LC Boccanfuso - 《University of Alberta》 被引量: 0发表: 1990年 Palladium- and Copper-Catalyzed Cross Coupling Reaction of Aliphatic Alcohols and Aryl Halides Alkyl aryl ethers are present in many naturally occurr...
In an embodiment of the presently claimed invention, the at least one base is selected from the group consisting of alkali metal amides, such as sodium amide and lithium diisopropylamide, alkali metal bis(trialkylsilyl)amides such as lithium bis-(trimethyl-silyl)amide and sodium bis-(trimethyl...