The meaning of AMES TEST is a test for identifying potential carcinogens by studying their mutagenic effect on bacteria. How to use Ames test in a sentence.
The preclinical genotoxicity study that focus on AMES test in vitro. The AMES test is a sensitive tool in screening for potential genotoxic carcinogens. Our genotoxicity study has professional teams with rich experience in toxicology studies. We offer high-quality data and rapid turnaround period to...
The principle behind the Ames test is based on the fact that many carcinogens are also mutagens, meaning they have the ability to cause changes in the DNA of cells. The test uses bacteria as the test organism, specifically strains of Salmonella typhimurium that are unable to grow in the abse...
(Biochemistry) a method of preliminary screening for carcinogens, based on their ability to cause mutations in bacteria [named after BruceAmes(born 1928), US biochemist who invented the test] Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991,...
Ames testCarcinogenicityEscherichia coliFrameshift mutationsGenetic toxicology batteryMutationa widely used test to detect possible chemical carcinogens; based on mutagenicity in the bacterium Salmonella; → see Mutagenicity test .doi:10.1007/978-3-211-89836-9_59Dr. med. Dr. phil. Gerhard Nahler...
Ames test词源英文解释 Bruce N. Ames born 1928 American biochemist The first known use of Ames test was in 1974 Ames test医学词典英英释义 Ames testnoun a test for identifying potential carcinogens by studying the frequency with which they cause histidine-producing genetic mutants in bacterial co...
Carcinogens are mutagens: a simple test system: Ames, Bruce N., William E. Durston, Edith Yamasaki and Frank D. Lee, Biochemistry Department, University of California, Berkeley, Calif. 94720 (U.S.A.)doi:10.1016/0165-1161(73)90209-4...
The detection of mutagens is important because they may also be either teratogens or carcinogens. Of a battery of short-term genetic assays, the Salmonella typhimurium /microsome test developed by Ames et al. 1 , 2 is the most commonly used genotoxicity test. Two- and threefold rules and ...
Ames test does not directly indicate the carcinogenic (cancer-causing) potential of the substance, however there is a good correlation between mutagen strength and carcinogen strength in rodent studies; approximately 75% of chemicals that have a positive Ames test are found to be rodent carcinogens....
Mutation Res. (1980) B.N. Ames et al. Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test Mutation Res. (1975) There are more references available in the full text version of this article.Cited...