所属专辑:细胞生物学名词解释 音频列表 1 选择性通透屏障(selectively permeable barrier) 22 2018-10 2 选择性RNA剪接(alternative RNA splicing) 47 2018-10 3 选择素(selectin) 34 2018-10 4 信号转导(signal transduction) 52 2018-10 5 信号序列(signal sequence) ...
网络可变;剪接;可变rna加工 网络释义
Alternative splicing is a process that enables a messenger RNA (mRNA) to direct synthesis of different protein variants (isoforms) that may have different cellular functions or properties. It occurs by rearranging the pattern of intron and exon elements that are joined by splicing to alter the mRN...
Autophagy and RNA alternative splicing are two evolutionarily conserved processes involved in overlapping physiological and pathological processes. However, the extent of functional connection is not well defined. Here, we consider the role for alternati
RNA splicing,is an important part of regulation of eukaryotic gene expression.The paper describes the characteristics,function and regulation of RNA splicing,alternative splicing genes,and identification of splicing forms.Some samples were taken to introduce the application of alternative RNA splicing.关键...
In the human genome, more than 90% of the human genes undergo alternative splicing, which participates in the entire life activity. Abnormal RNA splicing is closely associated with human diseases, including cancer. Cancer is still a serious public health concern as the second leading cause of ...
virescens, they are not shared with the equivalent nAChR subunit of Anopheles, which is considered to be an example of convergent evolution [17]. It is possible that different alpha6 isoforms may interact with distinct sets of receptor guidance cues. RNA editing and alternative splicing of the ...
Regulation of gene expression through alternative pre-mRNA splicing appears to occur in all metazoans, but most of our knowledge about splicing regulators ... Dauwalder,Amaya-Manzanares,Mattox - 《Proceedings of the National Academy of Sciences of the United States of America》 被引量: 222发表: ...
However, deriving accurate isoform expression from high-throughput RNA-seq data remains a challenging task. In this mini-review, we aim to illustrate I) mechanisms and regulation of alternative splicing, II) alternative splicing associated human disease, III) computational tools for the quantification ...
However, few models exist for how such splicing might be regulated, and some studies have concluded that NAGNAG splicing is purely stochastic and nonfunctional. Here, we used deep RNA-Seq data from 16 human and eight mouse tissues to analyze the regulation and evolution of NAGNAG splicing. ...