Protein binding is lower(～70%) than with most benzodiazepines because of itslower lipophilicity.α-Hydroxylation of the methyl group tothe methyl alcohol (a reaction analogous to benzylic hydroxylation)followed
Alprazolam produces additive CNS depressant effects when coadministered with other psychotropic medications, anticonvulsants, antihistaminics, alcohol and other drugs that produce CNS depression (7.1). The formulation requires an acidic environment to dissolve; therefore, drugs or diseases that cause dry ...
And while alprazolam is strong enough on its own, when it is abused in combination with alcohol, the effects are increased dramatically.To set the stage, it is important to note that in 2011, over 10% of all emergency department visits as a result of non-medical use of prescription drugs...
misuse, and addiction, which can lead to overdose or death. Abuse and misuse of benzodiazepines often (but not always) involve the use of doses greater than the maximum recommended dosage and commonly involve concomitant use of other medications, alcohol, and/or illicit substances, which...
Patients, Parents, and Caregivers Always tell your health care professionals about all the prescription and over-the-counter (OTC) medicines you are taking or any other substances you are using, including alcohol. Take benzodiazepines and all medicines exactly as prescribed by your health care profes...
Abuse and misuse are frequently associated with the use of medications above the maximum recommended dose, or together with other medications, alcohol, or illicit substances.Patients with a high risk for abuse should be advised about the proper use of alprazolam and be monitored for signs of ...
Alprazolam interacts with alcohol and medications (for example,barbiturates, and narcotics) that suppress activity in the brain by suppressing activity more and causing sedation. Carbamazepineand rifampin reduce the effect of alprazolam by increasing metabolism and elimination of alprazolam in theliver. ...
Xanax (generic name alprazolam) and Valium (generic name diazepam) are benzodiazepines (tranquilizers) used to treat anxiety and panic attacks. Valium is also used to treat agitation, tremors, delirium, seizures, and hallucinations resulting from alcohol
XANAX can make you sleepy or dizzy and can slow your thinking and motor skills.Do not drive, operate heavy machinery, or do other dangerous activities until you know how XANAX affects you. Do not drink alcohol or take other drugs that may make you sleepy or dizzy while taking XANAX without...
XANAX can make you sleepy or dizzy and can slow your thinking and motor skills.Do not drive, operate heavy machinery, or do other dangerous activities until you know how XANAX affects you. Do not drink alcohol or take other drugs that may make you sleepy or dizzy while taking XANAX without...