Confirmation of gestational exposure to alprazolam by analysis of biological matrices in a newborn with neonatal sepsis. Clin Toxicol 2007; 45(3): 295–8 CrossRef Rajkumar AP, Jebaraj P, Tharyan P. Multi-drug overdose risperidone, ziprasidone, valproate, trihexyphenidyl, and clonazepam. J Assoc...
The most frequent adverse drug reactions to benzodiazepines are drowsiness, depression, impaired intellectual function and memory, lethargy, impaired coordination, dizziness, nausea and/or vomiting, skin rash, and respiratory disturbance. Data from our study showed that sleep disorders, depressive disorders...
25.4.1 Adverse drug reactions versus reactions An adverse drug event (ADE) is defined as “an injury resulting from the use of a drug. This term incorporates harm with a causal link to the drug (that is, adverse drug reactions and overdoses or toxicities) and harm resulting from the inapp...
Elevated plasma concentrations of some of these drugs and may increase or prolong both the pharmacologic effects and/or adverse reactions to these drugs (eg, increased plasma concentrations of some of these drugs can lead to QT prolongation and ventricular tachyarrhythmias including occurrences of torsa...
Because fluoroquinolones have been associated with serious adverse reactions, reserve drug use in patients who have no alternative treatment options for the following indications: Acute bacterial sinusitis; acute bacterial exacerbation of chronic bronchitis Contraindications Hypersensitivity to moxifloxacin or any...
Table 3 Basic information on AEs related to Nusinersen. Full size table Risk signal detection In this study, the analysis of AE reports involving Nusinersen revealed adverse reactions associated with the drug across 27 SOCs. The study results showed that the five systems with the highest frequency...
Infliximab is contraindicated in any patient with tuberculosis or other severe infection, patients with moderate or severe heart failure or in patients with a history of hypersensitivity to infliximab. Infliximab has been associated with acute infusion-related reactions including anaphylactic shock and dela...
Not to exceed 50 mg q2Weeks No additional benefit was observed with dosages >50 mg of risperidone long-acting injection (IM); a higher incidence of adverse reactions was observed Do not titrate dose more frequently than q4Weeks IM (Risvan) Patients who are risperidone naïve: Establish ...
and psychotic reactions have progressed to suicidal ideations/thoughts and self-injurious behavior such as attempted or completed suicide; reactions may occur following the first dose; advise patients to inform their healthcare provider immediately if these reactions occur, discontinue treatment, and instit...
antihistamines, corticosteroids, beclomethasone, bronchodilators and many other classes of drugs. All of these drugs may have their own negative side effects. The net result is that the patient is subjected to many different types of reactions that complicate the effectiveness of the chemotherapy ...