alpha-synuclein, a member of the synuclein family, is predominately expressed in brain tissues, where it is the major component of Lewy bodies, the major hallmark of Parkinson's disease We analyzed the phylogenetics, gene structure, and effects of different forms of alpha-synuclein on in vitro...
Accession Number :NP_000336.1 GeneID:6622 Swiss Prot:P37840 科研背景: Alpha-Synuclein (SNCA) is expressed predominantly in the brain, where it is concentrated in presynaptic nerve terminals (1). Alpha-synuclein is highly expressed in the mitochondria of the olfactory bulb, hippocampus, striatum a...
Entrez Gene:59109只老鼠Omim:191315个人SwissProt:P04629人SwissProt:Q3UFB7小鼠SwissProt:P35739大鼠Unigne:406293人Unigene:80682只老鼠Unigene:39098只老鼠 重要注意事项:所提供的产品仅用于研究用途,不用于人体、治疗或诊断应用。 核突触蛋白α抗体Alpha-Synuclein产品图片: 组织/细胞:大鼠脑组织;4%多聚甲醛固定和...
Altered mRNA Splicing, Chondrocyte Gene Expression and Abnormal Skeletal Development due to SF3B4 Mutations in Rodriguez Acrofacial Dysostosis. Related Antibodies Catalog number Gene ID Antigen Name Application 22524-1-AP6531DATELISA, IHC, WB, IP ...
The meaning of ALPHA-SYNUCLEIN is a protein that is found primarily in neurons and accumulates to form Lewy bodies in people affected with Parkinson's disease and some forms of dementia. How to use alpha-synuclein in a sentence.
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease Science, 276 (1997), pp. 2045-2047 View in ScopusGoogle Scholar [21] M.G. Spillantini, M.L. Schmidt, V.M. Lee, J.Q. Trojanowski, R. Jakes, M. Goedert Alpha-synuclein in Lewy bodies Nature, 388 ...
Altered mRNA Splicing, Chondrocyte Gene Expression and Abnormal Skeletal Development due to SF3B4 Mutations in Rodriguez Acrofacial Dysostosis.Related AntibodiesCatalog number Gene ID Antigen Name Application 22524-1-AP 6531 DAT ELISA, IHC, WB, IP 18355-1-AP 5337 PLD1 ELISA, WB, IF, IP ...
SNCA (Synuclein Alpha) is a protein coding gene located on human chromosome 4q22.1. SNCA is also known as PD1, NACP, PARK1 and PARK4. The human SNCA gene encodes a 14460 Da protein containing 140 amino acids. The SNCA protein is biasedly expressed in brain, bone marrow and other tissue...
alpha-synuclein peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Multiple alternatively spliced transcripts encoding different isoforms have been identified for this gene. Diseases associated with SNCA include Parkinson Disease 1, Autosomal Dominant ...
alpha-synuclein peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Multiple alternatively spliced transcripts encoding different isoforms have been identified for this gene. Diseases associated with SNCA include Parkinson Disease 1, Autosomal Dominant and...