Alpha-Synuclein is a 14-19 kDa phosphoprotein primarily localized in the presynaptic terminals of mature neurons, where it is involved in synaptic function and plasticity. 2. Why is Alpha-Synuclein important? Alpha-Synuclein was the first missense mutation identified as a cause of familial Parkinson...
1. What is Alpha-Synuclein?Alpha-Synuclein is a 14-19 kDa phosphoprotein primarily localized in the presynaptic terminals of mature neurons, where it is involved in synaptic function and plasticity.2. Why is Alpha-Synuclein important?Alpha-Synuclein was the first missense mutation identified as a ...
2001 . α-synuclein. Axonal transport, ligand interaction and neurodegeneration . Adv. Exp. Med. Biol. 487 : 129 – 134 .Jensen P. H. and Gai W. P. ( 2001 ) Alpha-synuclein. Axonal transport, ligand interaction and neurodegeneration . Adv. Exp. Med. Biol. 487 , 129 – 134 ....
使用活性 α-突触核蛋白(alpha synuclein)蛋白聚合物和单体,轻松诱导神经元中的路易小体病理作用。适用于体外和体内实验。 路易士小体是帕金森病、路易士小体痴呆等疾病特征性的的神经细胞内α-突触核蛋白聚合物。路易士小体存在于负责运动控制的大脑区域,可导致心智能力逐渐下降。 图1.α-突触核蛋白原纤维聚合物通...
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Alpha Synuclein蛋白别名丰富，包括Alpha Synuclein Protein、AlphaSyn Protein、NACP Protein等。此蛋白在神经纤维缠结&Tau、突触核蛋白、神经生物学、神经衰退疾病、帕金森氏病及阿尔茨海默病研究领域有广泛应用。其在细胞核、细胞质及膜上有定位。相关研究文献及更多详情请咨询Stressmarq一级代理商-欣博盛生物...
Acta Pharmacol Sin Roflupram protects against rotenone-induced neurotoxicity and facilitates α-synuclein degradation in Parkinson's disease models. mouseWB, IHC, IF J Neurosci Mutant alpha-synuclein causes age-dependent neuropathology in monkey brain. ...
Our growing portfolio of Parkinson's Disease tools includes α-Synuclein Quantitative ELISA Kits (Human & Rat), for quantifying alpha-Synuclein in cell lysates and plasma.
Alpha-Synuclein Presynaptic neuronal protein alpha-synuclein has been linked both neuropathologically and genetically to Parkinson’s disease (PD). There are multiple ways in which α-synuclein could contribute to the etiology of Parkinson’s disease. However, the general consensus is that its ...