Testing for α-thalassemia includes: hematologic testing of red blood cell indices, peripheral blood smear, supravital stain to detect RBC inclusion bodies, and qualitative and quantitative hemoglobin analysis. HBA1, the gene encoding α1-globin, and HBA2, the gene encoding α2-globin, are the ...
Alpha thalassemia is one of the most common autosomal recessive disorders in the world. Alpha thalassemia is found in most populations worldwide, but is most common in the Middle East, Southeast Asia, and certain Mediterranean countries. [1]. The high birth prevalence rate of alpha thalassemia m...
A pregnant couple presented for evaluation of possible alpha thalassemia trait. Because both prospective parents were of Egyptian ancestry, routine screening for thalassemia trait was indicated. Hematologic testing showed that the mother was microcytic [mean red-cell volume (MCV) 75 fL] with a HbA2f...
Beta-Thalassemia -- GeneReviews(®) serum alpha-fetoprotein concentration for early detection of hepatocarcinoma in those with hepatitis C and iron overload; regular gallbladder echography for ear... RA Pagon,MP Adam,HH Ardinger,... - University of Washington, Seattle 被引量: 5发表: 1993年 ...
Tamary, H.; Dgany, O. Alpha-Thalassemia. InGeneReviews®; Adam, M.P., Everman, D.B., Mirzaa, G.M., Pagon, R.A., Wallace, S.E., Bean, L.J.H., Gripp, K.W., Amemiya, A., Eds.; University of Washington: Seattle, WA, USA, 1993–2022; pp. 1–24. Available online:...