A series of benzoquinolin-3-ones are pharmaceuticals effective in treating conditions consequent on both Type I and Type II 5 alpha -reductase. The compounds have the formula wherein R and R<1> both represent hydrogen or combine to form a bond; R<2> represents hydrogen or C1-C3 alkyl;...
中文别名 刺芒柄花素(485-72-3);芒柄花素;7-羟基-4-甲氧异苯酮;7-羟基-3-(4-甲氧苯基)色酮;7-羟基-4'-甲氧基异黄酮;生原禅宁B;芒柄花黄素;7-羟基-4`-甲氧基异黄酮 英文别名 Formononetin, Testosterone 5alpha-reductase inhibitor(CAS:485-72-3);Formononetin CAS号 485-72-3 SMILES OC1...
A 5 alpha -reductase inhibitor comprising as an effective component an extract from leaves and/or pericarps of a walnut. The inhibitor exhibits high potent 5 alpha -reductase inhibiting activity and high safety, and is thus effective in curing and preventing diseases caused by testosterone, e.g...
Purpose: To compare the clinical therapeutic efficacy of finasteride and dutasteride as 5-alpha reductase inhibitor (5-ARI) in the medical treatment of benign prostate hyperplasia. Materials and Methods: From July 2007 to July 2010, 354 benign prostatic hyperplasia patients with co...
Adherence to 5-alpha reductase inhibitor therapy for benign prostatic hyperplasia: clinical and economic outcomes Adherence to 5-alpha reductase inhibitor therapy for benign prostatic hyperplasia:clinical and economic outcomes. Gruschkus S,Poston S,Eaddy M, et al. P......
Prostate cancer patients can benef i t from5-alpha-reductase inhibitor treatment: ameta-analysisTuo Deng 1 , *, Xueming Lin 2 , *, Xiaolu Duan 1 , Zihao He 1 , Zhijian Zhao 1and Guohua Zeng 11 Department of Urology and Guangdong Key Laboratory of Urology, The First Aff i liated Hosp...
Dutasteride (GI198745, GG-745) is a dual 5-α reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone (DHT).
The effect of finasteride, a 5 alpha-reductase inhibitor, on scalp skin testosterone and dihydrotestosterone concentrations in patients with male pattern b... The effects of the 5 alpha-reductase inhibitor, , on scalp skin (T) and (DHT) levels were studied in patients with . In a double ...
Since it is not clear whether testosterone or dihydrotestosterone is the active hormone in bone metabolism, we wished to assess the effect of finasteride, a 5 alpha-reductase inhibitor, or vertebral bone mineral density and parameters of bone and mineral metabolism.Patients were treated in a randomi...
Disclosed herein are topical compositions of 5-α reductase inhibitors, such as dutasteride or finasteride, or a pharmaceutically acceptable salt, ester, or derivative thereof and th