G-protein alpha and beta-gamma subunits interact with conformationally distinct signaling states of rhodopsin. Vision Res. 46, 4442-4448.Downs, M,A.; Arimoto, R.; Marshall, G.R.; Kisselev, O.G. G-protein alpha and beta-gamma subunits interact with conformationally dis- tinct signaling ...
Alpha subunit Beta–gamma subunit complex Phototransduction Signaling 1. Introduction A prototypical seven transmembrane (7TM) domain receptor, rhodopsin, interacts with a heterotrimeric G-protein, transducin, to initiate a visual signaling cascade in response to light activation of rod photoreceptors (Har...
On the role of endogenous G-protein beta gamma subunits in N-type Ca2+ current inhibition by neurotransmitters in rat sympathetic neurones. 1. Using whole-cell and perforated-patch recordings, we have examined the part played by endogenous G-protein βγ subunits in neurotransmitter-mediated in....
The G protein alpha and beta-gamma subunits are capable of regulating various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit. Also known as: Adenylate cyclase stimulating G alpha Anti-G protein alpha抗体protein; Guanine nucleotide binding protein G(s)...
Identification of a G protein alpha subunit from Neurospora crassa that is a member of the Gi family. Heterotrimeric G proteins, consisting of alpha, beta, and gamma subunits, are implicated in major signal transduction pathways controlling a diversity of f... GE Turner,KA Borkovich - 《Journal...
Guanine nucleotide-binding proteins (G proteins) are modulators or transducers in various transmembrane signaling systems.Anti-G protein alpha 12抗体G proteins are composed of 3 subunits; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. ...
It appears that the single alpha subunit and the combined beta/gamma subunits form two active components capable of affecting the activity of downstream partners. Binding of adenosine to the A1 receptor causes the dissociation of the inhibitory G-protein alpha-subunit (Gi) from the complex, which...
In adult guinea pigs, the alpha-subunit at picomolar concentrations mediates the holo-G protein effect (Science Wash. DC 236: 442-445, 1987), but in chick embryo it has been reported that the beta gamma-dimer at nanomolar concentrations rather than the alpha-subunit is the effective mediator...
Heterotrimeric guanine nucleotide-binding proteins (heterotrimeric G proteins) are made up of alpha (Gα) , beta (Gβ) and gamma (Gγ) subunits. They act as molecular switches inside cells, and their main function is signal transduction working together with G protein-coupled ...
G alpha i-G alpha s chimeras define the function of alpha chain domains in control of G protein activation and beta gamma subunit complex interactions. 来自 NCBI 喜欢 0 阅读量: 26 作者:S Osawa,N Dhanasekaran,CW Woon,GL Johnson 摘要: Gs and Gi2 are G proteins whose alpha subunits are ...