(redirected from alpha-adrenergic receptors)Also found in: Thesaurus, Medical, Encyclopedia. re·cep·tor (rĭ-sĕp′tər) n. 1. Physiology A specialized cell or group of nerve endings that responds to sensory stimuli. 2. Biochemistry A molecular structure or site on the surface or ...
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family...
K+washout; These antagonists did not have a significant effect on LFS' inhibitory action on spike firing during EA.Conclusion:These findings suggest that LFS' anticonvulsant effect, on neuronal hyperexcitability following high-K+EA, may be mediated partly through α adrenergic receptors in hippocampal...
Alpha(2)-Adrenergic Receptorsdoi:10.1007/978-3-642-28753-4_200088The sympathetic nervous system is an involuntary system that plays an important role in normal physiological functions, such as control of body temperature and regulation of blood flow to various...Springer Berlin Heidelberg...
Alpha-blockers work by inhibiting alpha-1 adrenergic receptors on the smooth muscle cells of the bladder neck, prostate, and prostatic urethra, leading to the reduction in urethral resistance and bladder obstruction. Alpha-blockers prevent the sympathetic activation of these receptors...
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The alpha2-specific inhibitor, yohimbine, blocked this activation, thereby linking alpha2-adrenergic receptors to ASSC regulation via cAMP. The alpha1-specific ligand, terazosin, acted as an agonist and activated lymphocyte ASSCs but inhibited ASSC current that had been preactivated by norepinephrine ...
As is abundantly clear from the chapters contained in this volume, the combination of the receptor binding technique along with classical pharmacological methods has resulted in significant advances in our understanding of alpha-1 adrenergic receptors during the past 10 years. Because of the clinical ...
A commonly held view is that dopamine exerts its effects via binding to D1- and D2-dopaminergic receptors. However, recent data have emerged supporting the existence of a direct interaction of dopamine with adrenergic but this interaction has been poorly investigated. In this study, the pharmacolo...
Adrenergic receptors in rat brain microvessels were studied during ontogenesis. Microvessels were prepared by albumin floatation and glass bead filtration ... H Kobayashi,A Cazzaniga,P Spano,... - 《Brain Research》 被引量: 41发表: 1982年 Functional properties of suburothelial microvessels in the...