No association with the α1 antitrypsin phenotype MZ, as described by other authors, or with other phenotypes of this system was detectedGrabner G.2ndPausch V.2ndMayr W.R.2ndKargerOphthalmic ResGrabner G, Pausch V, Mayr WR. Alpha-l-antitrypsin pheno- types in acute anterior uveitis. ...
Obstructive lung disease and alpha1-antitrypsin deficiency gene heterozygosity Science (1969) RM Bruce et al. Collaborative study to assess risk of lung disease in Pi MZ phenotype subjects Am Rev Respir Dis (1984) J Lieberman This week's citation classic Current Contents (1983) J Lieberman et ...
Total alpha 1-antitrypsin was measured by the Mancini technique, and PI types were determined by isoelectric focusing. The MZ phenotype and the Z gene frequency were significantly more frequent in the urticaria group. The Z gene predominated in the groups with cold urticaria and acquired angio-...
A case history of a 16-year-old boy with and an intermediate deficiency of (MZ phenotype) is presented. Previous reports have suggested that may be associated with the Z variant of antitrypsin and either a severe or intermediate antitrypsin deficiency. The present case is unusual because of the...
Alpha-1 antitrypsin deficiency (AATD) is a significantly under-diagnosed genetic condition caused by reduced levels and/or functionality of alpha-1 antitrypsin (AAT), predisposing individuals to lung, liver or other systemic diseases. The management of individuals with the PI*MZ genotype, characterized...
The finding is recorded of typical a1-antitrypsin globules, confirmed by immunofluorescence and immunoperoxidase methods, in the hepatocytes of a patient shown to have a normal serum antitrypsin level and normal phenotype (TiM) for a1-antitrypsin. The identification of such globules can no longer be...
These results resemble those of a previous study in 66 male veterans with pulmonary emphysema suggesting that the MZ phenotype, or intermediate AAT deficiency in general, probably does predispose to the development of COPD. However, the prevalence of AAT deficiency in COPD patients is small (...
Individuals with severe alpha-1-antitrypsin (alpha1AT) deficiency (phenotype Pi ZZ) are abnormally liable to develop emphysema, but it is uncertain whether those with partial alpha1AT deficiency (phenotypes Pi MS and MZ) are similarly susceptible. This study was undertaken to determine the frequenc...
Role of alpha-1-antichymotrypsin deficiency in promoting cirrhosis in two siblings with heterozygous alpha-1-antitrypsin deficiency phenotype SZ Alpha-1-antitrypsin (A1AT) deficiency is the most common inherited metabolic disorder with the potential to cause injury in the lung and liver. Recent repo....
A 68-year-old woman with hepatic encephalopathy - Alpha(1)-antitrypsin deficiency, PZ phenotype 来自 ResearchGate 喜欢 0 阅读量: 49 作者:CL Berg,FM Graemecook,RE Scully,EJ Mark,LD Phillips 摘要: A 37-year-old woman was referred to the gastro-intestinal unit because of abnormal results of ...