alpha-1-antitrypsinbile ductsA child is reported whose alpha‐1 ‐antitrypsin phenotype is SZ and who has chronic cholestatic liver disease that began in the neonatal period. Liver biopsy demonstrated paucity of the interlobular bile ducts, marked hepatocellular deposition in periportal areas of PAS...
alpha1-Antitrypsin and alpha1-Antitrypsin Phenotyping(redirected from a1-AT phenotype) α1-Antitrypsin and α1-Antitrypsin Phenotyping Synonym/acronym: α1-antitrypsin: A1AT, α1-AT, AAT; α1-antitrypsin phenotyping: A1AT phenotype, α1-AT phenotype, AAT phenotype, Pi phenotype. Common use To...
pure magenta-coloured, sharply defined globules, 2-20 microns in diameter were found in periportal and paraseptal hepatocytes in all liver biopsies from eight alpha1-antitrypsin deficient (PiZZ) infants biopsied after the age of 12 weeks... IC Talbot,AP Mowat - 《Journal of Clinical Pathology》...
The effects of anticoagulants on the determination of both trypsin inhibitory capacity and the concentration of alpha 1-antitrypsin measured by radial immunodiffusion, and on the alpha 1-antitrypsin phenotype were investigated. These results were compared with those obtained for serum. The following anti...
This report describes the clinical characteristics of a group of 59 individuals with the PI*SZ phenotype and alpha 1-antitrypsin (alpha 1-AT) deficiency, identified during recruitment of a registry for subjects with severe alpha 1-antitrypsin deficiency. Currently, 1,129 individuals with levels of...
A 68-year-old woman with hepatic encephalopathy - Alpha(1)-antitrypsin deficiency, PZ phenotype 来自 ResearchGate 喜欢 0 阅读量: 95 作者:CL Berg,FM GraemeCook,RE Scully,EJ Mark,LD Phillips 摘要: A 37-year-old woman was referred to the gastro-intestinal unit because of abnormal results of ...
Alpha-1-antitrypsin deficiency: smoking, decline in lung function and implications for therapeutic trials Background: Alpha-1-antitrypsin (AT) deficiency is a hereditary disorder associated with pulmonary emphysema. AT replacement therapy has been available for... DCS Hutchison,D Cooper - 《Respir Med...
Kelly, J. KVasudev, K. SLee FI, Kelly JK, Vasudev KS (1983) Hepatic changes in a patient with alpha-l-antitrypsin deficiency (MZ phenotype). Portal tract elastosis and noncirrhotic portal hypertension. Arch Pathol Lab Med 107: 453–455...
IL‐1α cleavage by inflammatory caspases of the noncanonical inflammasome controls the senescence‐associated secretory phenotype Interleukin‐1 alpha (IL‐1α) is a powerful cytokine that modulates immunity, and requires canonical cleavage by calpain for full act... KA Wiggins,AJ Parry,LD Cassidy,...
Cells of adipose tissue are a source of molecules, collectively referred to as adipokines, including interleukin 6 (IL-6), tumor necrosis factor alpha (TNF-α), transforming growth factor beta (TGF-β), C-reactive protein (CRP), eotaxin, leptin, and adiponectin [37]. IL-6, as a ...