Alpha‐1‐antitrypsinZ variantChronic obstructive pulmonary diseaseLiver diseaseLaboratory testingClinical symptoms of 伪 -1-antitrypsin deficiency (AlATD) may originate either in the liver in children and adults or in the lung only in adults. Neonatal cholestasis, intrahepatic bile duct hypoplasia, ...
Alpha-1抗胰蛋白酶缺乏症的英文名字是Alpha-1 antitrypsin deficiency。基因解码表明:Alpha-1抗胰蛋白酶缺乏症是一种遗传性疾病,与基因突变密切相关。Alpha-1抗胰蛋白酶是一种由SERPINA1基因编码的蛋白质,它在肝脏中合成并通过血液循环分布到全身。该蛋白质的主要功能是
Alpha-1-antitrypsin deficiency (AATD) is a rare genetic disorder associated with the development of liver and lung disease. AAT is a 52-kD glycoprotein, produced mainly by hepatocytes and secreted into the blood. Agglomeration of the AAT-protein in hepatocytes can result in liver disease. Exposur...
So alpha-1 antitrypsin deficiency can lead to both emphysema and chronic bronchitis, the two types of chronic obstructive pulmonary disease, or COPD. 老慢支肺气肿,是否似成相识?不就是COPD嘛 Another, more common cause of COPD is smoking, and if someone with alpha-1 antitrypsin deficiency also s...
Alpha-1 antitrypsin(抗胰蛋白酶)deficiency is a genetic disorder(遗传病)in which a protein called alpha-1antitrypsin is defective or absent, and it causes lung and liver disease. α抗胰蛋白酶缺乏症是一种遗传性疾病,患者体内的一种叫做α抗胰蛋白酶的蛋白质出现了问题或者含量减少了,最终导致肺和肝脏...
α1-Antitrypsin is a glycoprotein of hepatic derivation, it constitutes an important serine protease inhibitor, responsible for the regulation of various serine proteinases, including trypsin, chymotrypsin, collagenase, elastase,cathepsin G, factor VIII, and kallicrein. Its deficiency has been associated...
doi:10.1080/21548331.1971.11706032HarveyUniversityL.UniversitySharpUniversityInformaworldHospital PracticeSharp H. L. Alpha-1-antitrypsin deficiency. Hosp Pract 1971 ; 6: 83 [Taylor & Francis Online]
genetic model of alpha-1-antitrypsin deficiency. chinese.eurekalert.org 圣路易大学儿童医学系塔克曼博士(Jeffrey Teckma)所领导的研究团队,证实了甲一型胰蛋白酵素抑 制剂 缺陷 动 物模 式中有氧化压力的产生。 chinese.eurekalert.org [...] and registered as having originated from the Liberian Camp ...
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Alpha-1-antitrypsin (α1AT) is a protease inhibitor, the deficiency of which is associated with premature emphysema and a wide spectrum of liver disease. This protein is a small glycoprotein that migrates electrophoretically with the α1-globulin fraction of serum. Alpha-1-antitrypsin is a prot...