alpha 1-Antitrypsin Deficiencyalpha 1-AntitrypsinAnti-Inflammatory Agents, Non-SteroidalSignal TransductionLung DiseasesNeutrophilsImmunity, InnateCell MovementAlpha-1 antitrypsin (AAT) has long been thought of as an important anti-protease in the lung where it is known to decrease the destructive effects...
中文名称:α-1抗胰糜蛋白酶抗体 英文名称:Anti-AACT-Alpha1 别名:Alpha-1-Antichymotrypsin; AACT-Alpha 1; AACT Alpha 1; SERPINA3; AACT; A1ACT; ACT; Alpha 1 Antichymotrypsin 1; Alpha 1 Antichymotrypsin 2; Alpha 1 Antichymotrypsin 3; Alpha 1 Antitrypsin Deficiency; Anti Elastase; Antichymotrypsin;...
Alpha-1 antitrypsin deficiency (AATD, OMIM #613490) is a rare metabolic disorder affecting lungs and liver. The purpose of this study is to assess the impact of the US orphan drug act on AATD by providing a quantitative clinical-regulatory insight into the status of FDA orphan drug approval...
Alpha-1-antitrypsin (A1AT) deficiency is the commonest genetic cause of liver disease in children and chronic obstructive lung disease in young adult smokers.The pathogenetic mechanisms are completely different. While low serum levels of A1AT cause reduced alveolar elasticity and subsequent emphysema,...
Involvement in Disease: Alpha-1-antitrypsin deficiency: A disorder whose most common manifestation is emphysema, which becomes evident by the third to fourth decade. A less common manifestation of the deficiency is liver disease, which occurs in children and ***s, and may result in cirrhosis...
Tamoxifen, an agent that binds to intracytoplasmic estrogen receptors, was evaluated as a possible means of increasing alpha-1-antitrypsin (alpha 1AT) synthesis and/or secretion and thus alpha 1AT serum levels in subjects with the homozygous form of alpha 1AT deficiency. Administration of tamoxifen...
别名重组人Serpin A1/alpha-1-Antitrypsin蛋白 | 重组人类 Serpin A1/alpha-1-抗胰蛋白酶蛋白 英文别名A1A | A1AT | AATMGC23330 | alpha 1-Antitrypsin | alpha 1-Proteinase Inhibitor | Alpha-1 protease inhibitor | Alpha-1-antiproteinase | alpha-1-antitrypsin | antitrypsin), member 1 | member 1...
Systemic modified messenger RNA for replacement therapy in alpha 1-antitrypsin deficiency Sci. Rep., 10 (2020), p. 7052 Google Scholar 38 Z.P. Parra-Guillen, A. Fontanellas, L. Jiang, D. Jericó, P. Martini, D. Vera-Yunca, M. Hard, L.T. Guey, I.F. Troconiz Disease pharmacokineti...
关键词: Liver Humans Cholestasis Liver Cirrhosis Pulmonary Emphysema Deficiency Diseases alpha 1-Antitrypsin Liver Transplantation Transplantation, Homologous Electrophoresis, Starch Gel 被引量: 1 年份: 1974 收藏 引用 批量引用 报错 分享 全部来源 求助全文 Semantic Scholar NCBI NCBI Europe PMC ResearchGate ...
alpha (alpha) cells alpha (alpha) chain alpha (alpha) fibers alpha (alpha) granule alpha (alpha) motor neuron alpha (alpha) particle alpha (alpha) rhythm alpha (alpha) thalassemia alpha (alpha)1 antitrypsin deficiency panniculitis alpha (alpha)1-antichymotrypsin alpha (alpha)1-antitrypsin deficien...