Antitrypsin alpha 1 deficiencyautopsyAlpha-1-antitrypsin deficiency of genotype PiZ was found in 15 persons (6.3 per cent) out of an autopsy series of 238. The hepatic tissue was screened after diastase digestion and PAS staining. The globules demonstrated thereby showed by the immunoperoxidase ...
Alpha-1抗胰蛋白酶缺乏症的英文名字是Alpha-1 antitrypsin deficiency。基因解码表明:Alpha-1抗胰蛋白酶缺乏症是一种遗传性疾病,与基因突变密切相关。Alpha-1抗胰蛋白酶是一种由SERPINA1基因编码的蛋白质,它在肝脏中合成并通过血液循环分布到全身。该蛋白质的主要功能是
Alpha-1-antitrypsin deficiency (AATD) is a rare genetic disorder associated with the development of liver and lung disease. AAT is a 52-kD glycoprotein, produced mainly by hepatocytes and secreted into the blood. Agglomeration of the AAT-protein in hepatocytes can result in liver disease. Exposur...
Those that consented to the study were subjected to a standardized questionnaire and have their Alpha-1-Antitrypsin level and genotype determined by the AlphaKit.Eleven patients, between the ages of 14 - 17 with a mean age of 16, participated in the study. They were all tall and thin and ...
【Osmosis】α-1抗胰蛋白酶缺乏症 Alpha-1 Antitrypsin Deficiency(中英字幕) 996 1 1:09 App 丝裂原活化蛋白激酶-MAPK(mitogen-activated protein kinase)-动画 16 -- 2:05 App 脂肪酸氧化缺乏 Fatty acid oxidation deficiency_PTH 8082 3 2:16 App 胰腺之歌(英文字幕) 757 -- 17:48 App (搬运油管...
Alpha-1 Antitrypsin Deficiency (A1AD) is a hereditary condition characterized by low levels of circulating alpha-antitrypsin (AAT) in plasma. It is the best understood genetic risk factor for the development of chronic obstructive pulmonary disease (COPD). The diagnosis of A1AD is under-recognized...
Alpha-1 antitrypsin(抗胰蛋白酶) deficiency is a genetic disorder(遗传病) in which a protein called alpha-1 antitrypsin is defective or absent, and it causes lung and liver disease. α抗胰蛋白酶缺乏症是一种遗传性疾病,患者体内的一种叫做α抗胰蛋白酶的蛋白质出现了问题或者含量减少了,最终导致肺...
Alpha1-antitrypsin deficiency (AATD) was first described by Laurell and Eriksson in 1963. Laurell noted the absence of the band of alpha1- protein in 5 of 1500 serum protein electrophoreses (SPEP) submitted to his laboratory in Sweden.
Alpha-1 antitrypsin deficiency (AATD, OMIM #613490) is a rare metabolic disorder affecting lungs and liver. The purpose of this study is to assess the impact of the US orphan drug act on AATD by providing a quantitative clinical-regulatory insight into the status of FDA orphan drug approval...
Alpha-1 antitrypsin(抗胰蛋白酶)deficiency is a genetic disorder(遗传病)in which a protein called alpha-1antitrypsin is defective or absent, and it causes lung and liver disease. α抗胰蛋白酶缺乏症是一种遗传性疾病,患者体内的一种叫做α抗胰蛋白酶的蛋白质出现了问题或者含量减少了,最终导致肺和肝脏...