Latent α<inf>1</inf>-antichymotrypsin. A molecular explanation for the inactivation of α<inf>1</inf>-antichymotrypsin in chronic bronchitis and emphysema 1998, Journal of Biological Chemistry Show abstract Stimulatory effect of inflammatory cytokines on α<inf>1</inf>-antichymotrypsin expression in...
The consequent lack of plasma antithrombin, C1-inhibitor and a1-antichymotrypsin results in thrombosis, angio-oedema and emphysema, respectively. Moreover, the polymerisation of mutants of neuroserpin results in the retention of polymers within neurones to cause the inclusion body dementia, familial ...
alpha1-Antitrypsin (alpha1AT) provides the major protection in the lung against neutrophil elastase-mediated proteolysis. Inheritance of alpha1AT deficiency alleles is associated with an increased risk of emphysema and liver disease. alpha1AT null alleles cause the total absence of serum alpha1AT an...
Screening and identification of tissue-infiltrating immune cells and genes for patients with emphysema phenotype of COPD Authors - Di Wang View Article human WB,IHC Br J Cancer Identification of GlcNAcylated alpha-1-antichymotrypsin as an early biomarker in human non-small-cell lung cancer by quant...
The S form is the most common variant of the serum protein α 1 antitrypsin, more than 5% of Northern Europeans being heterozygotes (MS) for the S and normal M alleles. The S variant results in a mild deficiency of antitrypsin that may be sufficient to predispose to emphysema in either ...
Protease inhibitors, such as alpha1-antitrypsin (A1AT) and alpha1-antichymotrypsin (A1AChy) have been considere... Krystyna,Bernacka,MD,... - 《Cancer》 被引量: 134发表: 1988年 Is an integrative laboratory algorithm more effective in detecting alpha-1-antitrypsin deficiency in patients with pr...
Alpha 1 Antitrypsin, Human Plasma 英文名称: Alpha 1 Antitrypsin, Human Plasma 总访问: 345 国产/进口: 进口 半年访问: 28 产地/品牌: Athens 产品类别: 分子生物学试剂 规格: 16-16-011609 最后更新: 2024-12-5 货号: CAS 号: 参考报价: 询价 立即询价 电话咨询 ...
Alpha-1-antitrypsin (A1AT) deficiency is the commonest genetic cause of liver disease in children and chronic obstructive lung disease in young adult smokers.The pathogenetic mechanisms are completely different. While low serum levels of A1AT cause reduced alveolar elasticity and subsequent emphysema,...
The association rate constants for the interaction of alpha-1-proteinase inhibitor, oxidized alpha-1-proteinase inhibitor, and alpha-1-antichymotrypsin wit... K Beatty,J Bieth,J Travis - 《Journal of Biological Chemistry》 被引量: 1242发表: 1980年 The serpin alpha1-proteinase inhibitor is a cri...
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