Alpha-1-antitrypsin and the pathogenesis of emphysema. Lung. 1987;165(1):61-77.Stockley RA (1987). Alpha-1-Antitrypsin and the pathogene- sis of emphysema. Lung 165:61-77.Stockley RA: alpha-1-antitrypsin and the pathogenesis of emphysema. Lung 165. (2): 61-77.1987; Citation...
Human alpha1 antitrypsin (Cat # 7294)来源宿主 兔反应性 经检测验证,可与人、小鼠、大鼠种属来源的Alpha1 Antitrypsin蛋白发生免疫反应.保存建议 提供的Alpha1 Antitrypsin抗体产品为无色液体.建议使用冰袋运输,收到产品后,请-20ºC储存.该产品有效期为12个月.其他...
Aim : To determine the cause of complete absence of alpha-1-antitrypsin in a patient who at age 27 years had both emphysema and idiopathic cardiomyopathy. Methods : Molecular biology techniques were used to sequence the alpha-1-antitrypsin gene. Allele specific amplification was used to show the...
Although alpha1-antitrypsin (AAT) deficiency typically causes emphysema, it also can produce airway obstruction with no evidence of alveolar destruction. Thus, the progressing disease and the growing risk of emphysema may go undiagnosed for years in patients with asthma. In this article, the authors...
So alpha-1 antitrypsin deficiency can lead to both emphysema and chronic bronchitis, the two types of chronic obstructive pulmonary disease, or COPD. 老慢支肺气肿,是否似成相识?不就是COPD嘛 Another, more common cause of COPD is smoking, and if someone with alpha-1 antitrypsin deficiency also ...
So alpha-1 antitrypsin deficiency can lead to both emphysema and chronic bronchitis,the two types of chronic obstructive pulmonary disease, or COPD. 老慢支肺气肿,是否似成相识?不就是COPD嘛 Another, more common cause of COPD is smoking, and if someone with alpha-1 antitrypsin deficiencyalso smoke...
Elastase, Collagenase, Emphysema, and Alpha 1 -Antitrypsin DeficiencyThe various experiments and studies reviewed suggest that the elastic tissue of lung and the elastolytic enzymes of leukocytes are primarily involved in the pathogenesis of emphysema. Cutis laxa is a genetic model in man that shows...
Alpha-1-antitrypsin (α1AT) is a protease inhibitor, the deficiency of which is associated with premature emphysema and a wide spectrum of liver disease. This protein is a small glycoprotein that migrates electrophoretically with the α1-globulin fraction of serum. Alpha-1-antitrypsin is a prot...
Alpha1-antitrypsin deficiency (AATD) was first described by Laurell and Eriksson in 1963. Laurell noted the absence of the band of alpha1- protein in 5 of 1500 serum protein electrophoreses (SPEP) submitted to his laboratory in Sweden.
Alpha-1-antitrypsinProteaseAntiproteaseLiver diseaseChronic obstructive pulmonary disease (COPDTwo disparate disease states—an adult form of emphysema and a childhood form of liver cirrhosis—have been linked to an inherited absence of this antienzyme. In their severe, homozygous forms, both conditions...