ALMS1-IT1在结直肠癌中的表达及其对癌细胞增殖、侵袭和上皮间质转化的影响 论 著?基础研究?ＡＬＭＳ１－ＩＴ１在结直肠癌中的表达及其对癌细胞增殖、侵袭和上皮间质转化的影响 王浩艺１，２，刘 畅１，孙学军１ ＴｈｅｅｘｐｒｅｓｓｉｏｎｏｆＡＬＭＳ１－ＩＴ１ｉｎｃｏｌｏｒｅｃｔａｌｃａｎｃｅｒａ...
ALMS1-IT1biomarkerLncRNA.Colon adenocarcinoma (COAD) is one of the most serious cancers. It is important to accurately predict prognosis and provide individualized treatment. Evidence suggests that clinicopathological features and immune status of the body are related to the occurrence and development ...
Knockdown of ALMS1-IT1 inhibited the PPP, contributing to a decline in NADPH levels, which resulted in the formation of multiple intermolecular disulfide bonds between actin cytoskeleton proteins and the collapse of F-actin in the cytoplasm. Therefore, ALMS1-IT1, which is...
预测ALMS1-IT1相互作用的分子,采用qRT-PCR和蛋白质印迹法检测这些分子的表达情况.结果结直肠癌组织中ALMS1-IT1的相对表达量较癌旁组织增加(4.54±0.61比1.19±0.31;t=34.89,P<0.01).40例患者癌组织中ALMS1-IT1中位相对表达量为2.93,ALMS1-IT1高表达率为50.0%(20/40).TNM分期Ⅲ期患者癌组织ALMS1-IT1高...