thesyn-hydroxy ether31as a single isomer after onecrystallization. The selectivity of the ring-opening of31has been attributed to participation of theortho-oxygen lone-pairs in epoxide ring-opening, followed by nucleophilic attack by MeOH at the benzylic positon opposite the bulkyn-pentyl side-...
Synthesis of branched or linear prenylated benzylic imines. Recently, O’Broin and Guiry63 established the palladium-catalyzed synthesis of 2-amino-1,3-dienes 93 from the propargylic precursors 92 (Scheme 42). The mild reaction conditions showed broad functional group tolerance. Various amine ...