HLA-BFNx015801Allopurinol, a drug commonly used for treating gout and hyperuricemia, is a frequent cause of drug eruptions. Recent investigations suggest that HLA-B*5801 allele is a very strong marker for allopurinol-induced cutaneous adverse drug reactions (cADRs). In this article we report ...
Consider screening for HLA-B*5801 before starting treatment with allopurinol tablets in patients from populations in which the prevalence of this HLA-B*5801 allele is known to be high. Screening is generally not recommended in patients from populations in which the prevalence of HLA-B*58:01 is ...
Presence of the HLA-B*5801 allelic variant is strongly associated with severe allopurinol-induced hypersensitivity reactions, particularly in certain Asian populations. (See Pharmacogenomics of Allopurinol-induced Hypersensitivity Reactions under Cautions.) However, other genetic or nongenetic factors (e.g.,...
Consider screening for HLA-B*5801 before starting treatment with allopurinol tablets in patients from populations in which the prevalence of this HLA-B*5801 allele is known to be high. Screening is generally not recommended in patients from populations in which the prevalence of HLA-B*58:01 is ...
来源期刊 台湾实证医学学会会刊 研究点推荐 Allopurinol过敏基因HLA-B*5801检测 站内活动 0关于我们 百度学术集成海量学术资源,融合人工智能、深度学习、大数据分析等技术,为科研工作者提供全面快捷的学术服务。在这里我们保持学习的态度,不忘初心,砥砺前行。了解更多>>...
Saokaew S, Tassaneeyakul W, Maenthaisong R, Chaiyakunapruk N. Cost-effectiveness analysis of HLA-B*5801 testing in preventing allopurinol-induced SJS/TEN in Thai population. PLoS One 2014;9:e94294.Saokaew S, Tassaneeyakul W, Maenthaisong R, et al. Cost-effectiveness analysis of HLA-B*...
Analysis o价罪金情氢直争谈船刻降f allopuri存永电慢浓苗担风耐nol medication and hla-b* 5801 genotyp飞界接干歌乙乎秋ing of patients with drug eruption. 别嘌呤醇用药调查及其药疹患者hla-b*5801基因型分析。3.Allopurinol is a drug used in uric acid and calcium stone removal. 别嘌醇是一种...
Genetic Testing (HLA B5801) prior to use if Hans Chinese, Thai or if CKD 3, Korean Stop Allopurinol if this occurs Increased risk when concurrent use ofBendamustine,Thiazide Diuretics,AmpicillinorAmoxicillin Toxic Hepatitis Gastrointestinal (Nausea,Diarrhea) ...
HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol Our results indicated that allopurinol-SCAR is strongly associated with a genetic predisposition in Han Chinese. In particular, HLA-B*5801 allele is an ... SL Hung,WH Chung,LB Liou,... - 《Pr...
2.Analysis of a来自llopurinol medication and hla-b* 5801 genotyping 因风of patients w360问答ith drug eruption. 别嘌呤醇用药调查及其药疹患者hla-b*5801基因型分析。3.Allopurinol is a drug used in uric acid and calcium stone removal. 别嘌醇是一种药物使用的尿酸和钙结石清除。