Consider screening for HLA-B*5801 before starting treatment with allopurinol tablets in patients from populations in which the prevalence of this HLA-B*5801 allele is known to be high. Screening is generally not recommended in patients from populations in which the prevalence of HLA-B*58:01 is ...
HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol. Proc Natl Acad Sci U S A. 2005;102(11):4134-4139.Hung, S.L.; Chung W.H.; Liou L.B.; Chu C.C.; Lin, M.; Huang, H.P.; Lin, Y.L.; Lan, J.L.; Yang, L.C.; Hong, ...
Presence of the HLA-B*5801 allelic variant is strongly associated with severe allopurinol-induced hypersensitivity reactions, particularly in certain Asian populations. (See Pharmacogenomics of Allopurinol-induced Hypersensitivity Reactions under Cautions.) However, other genetic or nongenetic factors (e.g.,...
Consider screening for HLA-B*5801 before starting treatment with allopurinol tablets in patients from populations in which the prevalence of this HLA-B*5801 allele is known to be high. Screening is generally not recommended in patients from populations in which the prevalence of HLA-B*58:01 is ...
来源期刊 台湾实证医学学会会刊 研究点推荐 Allopurinol过敏基因HLA-B*5801检测 站内活动 0关于我们 百度学术集成海量学术资源,融合人工智能、深度学习、大数据分析等技术,为科研工作者提供全面快捷的学术服务。在这里我们保持学习的态度,不忘初心,砥砺前行。了解更多>>...
Saokaew S, Tassaneeyakul W, Maenthaisong R, Chaiyakunapruk N. Cost-effectiveness analysis of HLA-B*5801 testing in preventing allopurinol-induced SJS/TEN in Thai population. PLoS One 2014;9:e94294.Saokaew S, Tassaneeyakul W, Maenthaisong R, et al. Cost-effectiveness analysis of HLA-B*...
Drug eruptions induced by allopurinol associated with HLA-B*5801. Indian Journal of Dermatology, Venereology and Leprology 81: 43-45, No. 1, Jan 2015 - China Article PubMed Google Scholar Download references Rights and permissions Reprints and permissions About this article Cite this article ...
Genetic Testing (HLA B5801) prior to use if Hans Chinese, Thai or if CKD 3, Korean Stop Allopurinol if this occurs Increased risk when concurrent use ofBendamustine,Thiazide Diuretics,AmpicillinorAmoxicillin Toxic Hepatitis Gastrointestinal (Nausea,Diarrhea) ...
Analysis o价罪金情氢直争谈船刻降f allopuri存永电慢浓苗担风耐nol medication and hla-b* 5801 genotyp飞界接干歌乙乎秋ing of patients with drug eruption. 别嘌呤醇用药调查及其药疹患者hla-b*5801基因型分析。3.Allopurinol is a drug used in uric acid and calcium stone removal. 别嘌醇是一种...
Stevens-Johnson syndrome (SJS)/Toxic epidermal necrolysis (TEN) can still occur in patients who are found to be negative for HLA-B*5801 irrespective of ethnic origin. 13 NONCLINICAL TOXICOLOGY 13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility ...