Allele (biology definition):variant of a gene controlling the same trait and occupying a specific region on a chromosome (called the locus).Etymology:from Greek ἄλλος (állos), meaning “other”.Synonyms:allelomorph. Allele Examples Below are examples of alleles and how they are expres...
The number of allelic forms of a gene can be many (MULTIPLE ALLELISM), each form having a slightly different sequence of DNA bases but with the same overall structure. Each diploid can, however, carry only two alleles at one time. See also DOMINANCE (1). Collins Dictionary of Biology, ...
Define Mutant allele. Mutant allele synonyms, Mutant allele pronunciation, Mutant allele translation, English dictionary definition of Mutant allele. n. 1. The act or process of being altered or changed. 2. An alteration or change, as in nature, form, or
Allele-level characterization of telomeres provides a foundation for future studies to contrast samples with abnormal ATLs against baseline ATL distributions. For example, in the context of telomere biology disorders it is largely unknown whether low average TL, shortening of a specific telomere, or sh...
Note that, by definition, if the null hypothesis of a statistical test is true, then the probability that a P value is less than or equal to a will be a as well. This implies that, under the null hypothesis, a statistically sound hypothesis testing method must produce P values that are...
et al. Molecular definition of breast tumor heterogeneity. Cancer cell. 11, 259–273 (2007). 7. Brock, A., Chang, H. & Huang, S. Non-genetic heterogeneity--a mutation- independent driving force for the somatic evolution of tumours. Nat Rev Genet. 10, 336–342 (2009). 8. Marusyk,...
Among African Americans with large apo[a], the allele-specific apo[a] level was significantly lower among ε2 carriers compared with ε3 or ε4 carriers (5.4 vs. 6.6 and 7.4 nmol/l, respectively; P < 0.005, expressed as square root levels). In contrast, there was no significant ...
The simplest definition of cis-eQTLs versus trans, refers to genetic variants that affect expression in an allele specific manner, with implications on underlying mechanism. Yet, due to technical limitations of expression microarrays, the vast majority o
The population genetics definition of 'heritability' in a parent–offspring setting is described by the slope, b, of a regression (Y ¼ bX þ a), with the dependent variable being the child's trait value (Y) and the independent variable (X) being the average trait values of the ...
HLA typing and definition of HLA disparity HLA alleles were typed at the resolution level of the second field using polymerase chain reaction-sequence-specific oligonucleotide (PCR-SSO) method or sequence-based typing (SBT). HLA allele mismatches in the GVH direction were scored when the patient’...