Small molecules and proteins can inhibit topoisomerase activity at different stages of the topoisomerase catalytic cycle. Inhibition of topoisomerases has been exploited in therapeutics and in nature. Abstract Topoisomerases are complex molecular machines that modulate DNA topology to maintain chromosome super...
According to the mode of action, three main types of antioxidants are known: (a) those preventing the formation of new free radicals, (b) those making them less harmful before they can react, and (c) those preventing the formation of free radicals from other molecules. The enzymes involved...
It takes place in the mitochondria of the cells. It produces a large amount of ATP molecules via substrate-level phosphorylation. The major significance of this cycle is to act as the final common pathway of all lipids, glucose, and pr...
In the latest tapping mode AFM, the cantilever is oscillated at high frequency; 3D topography of the surface can be generated under milder scanning conditions. For the other way, we can utilize the nanomanipulation of the AFM to see the interaction between inner molecules, and realize the ...
Biomolecules in cells fall under one of the four categories: proteins, nucleic acids, carbohydrates, lipids. Nucleic acids are molecules that contain nucleotide monomers, such as adenine, uracil, guanine, thymine, and cytosine. Answer and Explanation: Beco...
Testing for Biological Molecules The Earth BioGenome Project (EBP) The Five Study Tips for Pharmacology to Ace Your Grades in Nursing School The Germ Theory of Disease The Human Digestive System: Organs, Functions, Diagram The Human Genome Project The Michaelis–Menten Model The Ontario Curriculum ...
The ATP-Binding Cassette Transporter ABCA4: Structural and Functional Properties and Role in Retinal Disease ATP-binding cassette transporters (ABC transporters) utilize the energy of ATP hydrolysis to translocate an unusually diverse set of substrates across cell... Y Tsybovsky,RS Molday,K Palczew...
(Fig.2H, I). Gel 3 presented the largest fracture energy, as a result of balance in compressive stress and flexibility (Fig.2J). Moreover, the swelling ratio of Gels 3 and 4 was larger than that of Gels 1 and 2 (Supplementary Fig.3), and their stability was also improved compared ...
aIn contrast, fatty acids are several-fold more energy rich than glucose, with oxidation of the fatty acid palmitate capable of generating 106 ATP molecules. 相反,脂肪酸比葡萄糖several-fold能源丰富,以脂肪酸软脂酸的氧化作用能引起106个ATP分子。[translate] ...
Johannes von Lintig, in Methods in Enzymology, 2022 1 Introduction Vitamin A (all-trans-retinol) is converted by endogenous pathways to metabolites that exert physiological functions as chromophores and signaling molecules (von Lintig, Moon, & Babino, 2021; Widjaja-Adhi & Golczak, 2020). The ...