Self-assembly of copper sulfate and a poly(imidazole-acrylamide) amphiphile provides a highly active, reusable, globular, solid-phase catalyst for click chemistry. The insoluble amphiphilic polymeric imidazole Cu catalyst drove the cycloaddition of variou...
A novel dinuclear copper complex CuI2(pip)2 was used as a catalyst for alkyne–azide cycloaddition (CuAAC) reaction. High yields (95–99%) were obtained for various substrates at a low loading of 0.2 mol %. The unique structure, high stability of the dinuclear structure in solution,...
点击反应是一种高效、特异性和快速的化学反应,可用于将CY7 alkyne荧光染料与含有Azide官能团的生物分子特异性地结合。该反应称为"Copper(I)-catalyzed Azide-Alkyne Cycloaddition"(CuAAC),通常简称为点击反应。这个反应的关键步骤涉及铜催化的炔烃和偶氮化物的环加成,生成1,2,3-三氮唑环。 点击反应的步骤如下: 1...
A copper (I)-catalyzed azide-alkyne cycloaddition (CuAAC) grafting-to method was used to tether alkyne-terminated poly(2-acrylamido-2-methyl propane sulfon... Y Wang,LL Wang,XC He,... - 《Journal of Colloid & Interface Science》 被引量: 6发表: 2014年 Synthesis of novel 1,2,3-triazol...
Alkyne-Azide CycloadditionsGlembockyte, Viktorija
The most famous amongst them is the copper-catalyzed azide-alkyne cycloaddition (CuAAC) which opens up outstanding opportunities in various fields of science and technology. Since the development of the CuAAC by Meldal and Sharpless it gained enormous attention not only in the field of chemistry,...
Here we compare the conjugation of a model antibody and of streptavidin to the surface of biocompatible 100 nm magnetic starch nanoparticles by strain-promoted alkyne-azide cycloaddition (SPAAC) with the established carbodiimide and maleimide chemistry. Under our reaction conditions the bioreactivity of ...
Copper-catalyzed alkyne-azide cycloaddition… 来自 iupac.org 喜欢 0 阅读量: 21 作者: Nierengarten, JeanFrançois 摘要: In this paper, we report our ongoing progress in the preparation of fullerene-azide or fullerene-alkyne building blocks, allowing their further chemical under the copper-...
Proceeding Paper Synthesis of 1,2,3-Triazoles from Alkyne-Azide Cycloaddition Catalyzed by a Bio-Reduced Alkynylcopper (I) Complex † Josué Varela-Palma 1, Jaime González 1, Gustavo Lopez-Téllez 1,2, M. V. Basavanag Unnamatla 1,2, Marco A. García-Eleno 1,2 and Erick Cuevas-...
IR825 alkyne中IR-825是一种近红外染料(NIR)。IR-825在封装成纳米颗粒后,可能用于癌症光热和光动力治疗。IR-825纳米颗粒显示出pH依赖性荧光发射和近红外(NIR)辐射。 炔烃(alkyne)是常用生物标记基团,通过铜催化点击化学反应(Copper-catalyzed azide–alkyne cycloaddition, CuAAC),炔烃可以和叠氮(azide)生成稳定的生...