dimethindeneenantioseparationpharmaceutical analysispheniramineCyclodextrin-mediated capillary isotachophoresis (ITP) in cationic regime of the separation was developed for the separation and quantitation of alkylamine antihistamine dimethindene (DIM) and pheniramine (PHM) enantiomers in various pharmaceutical ...
In accordance with this invention, there is provided a group of antihistamine agents of the formula: ##STR3## in which A is a 3,4-; 3,2-; or 2,3-fused thieno-moiety or a benzo-moiety; X is alkylene of 2 to 5 carbon atoms; ...
Thus, the inhibition of TRPV1 activation by dexbrompheniramine may provide one potential mechanism whereby this antihistamine exerts its therapeutic effect in chronic cough.doi:10.1080/01902140802339623Sadofsky, Laura R.Campi, BarbaraTrevisani, Marcello...
Process for the preparation of novel benzhydryloxyalkylamine derivatives with delayed antihistamine actionThe compounds of the general formula (I) in which X = halogen atom, methyl or methoxy groups; n = 2, 3 or 4; A = together with a nitrogen atom a partially or completely saturated ...
A pharmaceutical preparation comprising a first generation antihistamine, more particularly an alkylamine, preferably chlorphenamine, in combination with a (preferably mild) herbal sedative, preferably valerian, St Johns wort, passiflora and/or green tea extract. This is preferably in combination with ...
In the formula (II), Y = halogen atom or hydroxyl group and m = 2, 3 or 4. The compounds of the general formula (I) and their acid addition salts have a delayed antihistamine effect.IVAN BECKJOZSEF RAKOCZIKALMAN BOLLAKATALIN PORSZASZ...
A pharmaceutical preparation comprising a first generation antihistamine, more particularly an alkylamine, preferably chlorphenamine, in combination with a (preferably mild) herbal sedative, preferably valerian, St Johns wort, passiflora and/or green tea extract. This is preferably in combination with ...
In the formula (II), Y = halogen atom or hydroxyl group and m = 2, 3 or 4. < IMAGE > The compounds of the general formula (I) and their acid addition salts have a delayed antihistamine effect.
In the formula (II), Y = halogen atom or hydroxyl group and m = 2, 3 or 4. The compounds of the general formula (I) and their acid addition salts have a delayed antihistamine effect.
Compounds of Formula I exhibit antihistamine activity and form with a conventional carrier a pharmaceutical composition which may be administered orally or parenterally.