(a substance that renders other matierial inactive or ineffective). Only "free" histamine would produce allergic symptoms, so an antagonist (opposite) to this free histamine had to be found. Bovet could not discover a natural antagonist to histamine, so he looked for substances that were similar...
Some additional clinical parameters were also recorded: days of school absence, extra visits for acute respiratory symptoms, and days of hospital admission. Results: Only children treated with terfenadine achieved significant control of symptoms ( P <0.05 in 8 out of 12 months) and allergic ...
Diphenhydramine (Benadryl) is an antihistamine used for treatingallergicreactions. Histamine is released by the body during several types of allergic reactions and—to a lesser extent—during some viral infections, such as thecommon cold. When histamine binds to receptors on cells, it stimulates chang...
14、antihistaminedrugs can be used to reduce inflammation when it is caused by an allergic reaction.(抗组织胺药物,可以用来减轻炎症时,这是造成过敏反应。) 15、Taking anantihistamineisn't the only way to battle seasonal allergies.(采取抗组织胺并不是唯一防止季节性过敏的方法。) ...
while ensuring adequate relief of allergic conditions. The explanation for their peripheral selectivity is, many of these compounds are zwitterionic at physiological pH levels (around 7.4 pH). They are very polar, which indicates that they are less likely to cross the blood-brain barrier and functi...
All documented allergic-like reactions to i.v. gadolinium-containing contrast media after premedication with corticosteroids and antihistamines were identified. Forms were evaluated for reaction manifestations, management, and patient outcome. Our institutional electronic medical record system was accessed for ...
19. I had an allergic reaction to my antihistamine medication. 我对抗组胺剂的药物有过敏。 20. Fexofenadine was the second era antihistamine drug used to treat anaphylaxis, and was not sedative and heart toxicity. 非索非那定是第二代抗组胺药物,用于治疗过敏性疾病,无嗜睡,无心脏毒性,副作用小。
Second generation of H(1)-antihistamines are the drugs of choice for allergic responses because of their high selectivity to H1 receptors, high efficacy, and minimal side effects. The half-life in plasma depends on drug metabolism and elimination processes in the body. The process is the same ...
The body's reaction to histamine is characterized by contraction of smooth muscle, signs of inflammation, constriction of vessels, and symptoms characteristic of shock. It is certain that histamine plays a central role in allergic reactions, hypersensitivity reactions, and is part of the body's ...
Use of antihistamine for an occasional urticarial rash may be justified. Histamine is the substance that is produced as a result of the allergic reaction in the body, which finally leads to rash and itching.