Gene ID (NCBI) 238 RRID AB_2881432 偶联类型 Unconjugated 形式 Liquid 纯化方式 Protein A purification UNIPROT ID Q9UM73 储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 储存条件 Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC sto...
Full Name anaplastic lymphoma receptor tyrosine kinase Synonyms ALK, ALK tyrosine kinase receptor, Anaplastic lymphoma kinase, CD246, TFG/ALK Calculated Molecular Weight 1620 aa, 176 kDa GenBank Accession Number NM_004304 Gene Symbol ALK Gene ID (NCBI) 238 RRID AB_2881432 Conjugate Unconjugated F...
Full Nameanaplastic lymphoma receptor tyrosine kinase Calculated Molecular Weight1620 aa, 176 kDa GenBank Accession NumberNM_004304 Gene SymbolALK Gene ID (NCBI)238 RRIDAB_2881432 ConjugateUnconjugated FormLiquid Purification MethodProtein A purification ...
ALKgene rearrangement can manifest in the form of a translocation with another partner gene leading to formation of a fusion oncogene. These fusions often arise from fusion of the 3′ end of theALKgene (exons 20–29) with the 5′ portion of a different gene92. For example, in some NSCLC...
(ssDNAs) form the foundation of aptamer-linked DNA nanoparticles, ensuring exceptional stability, cell type-specific penetration, and dependable control. Furthermore, the intricate integration of diverse DNA cascade circuits demonstrates the enhanced sensing capabilities of DNA nanoparticles during live cell...
Identifying ALK+ NSCLC patients for targeted treatment The VENTANA ALK (D5F3) CDx Assay empowers your lab to provide timely results with a four-and-one-half hour run time using fully automated, ready-to-use reagents. Technical benefits of IHC testing ...
A screening method for the ALK fusion gene in NSCLC. Front Oncol. 2012;2:24. 25. Camidge DR, Skokan M, Kiatsimkul P, et al. Native and rear- ranged ALK copy number and rearranged cell count in non-small cell lung cancer: implications for ALK inhibitor therapy. Cancer. 2013;119(22)...
Full size image Gilteritinib exhibited potent antitumor activity against patient-derived cancer cells Next, we checked whether gilteritinib displayed antitumor activity againstALK-rearranged human NSCLC cells. Using cell viability assays, we confirmed the potent activity againstEML4-ALKfusion gene (WT,...
Intriguingly, the newly formed sex chromosomes were found to have originated from the fusion of two autosomal chromosomes, showcasing a highly rearranged segment with an SDR gene situated downstream of the fusion site. Examination of the Y chromosome unveiled an early stage of differentiation, without...
inhibits the function of an individual target gene, aswell as overexpression powered by mRNA shot, can transform the known degrees of particular focus on genes. The injected egg could be after that grown to several levels from early blastula levels to tadpole levels (within 3 times), after ...