and Day, E.A. 1965 . Aldehyde-amine condensation reaction; a possible fate of carbonyls in foods . J. Food Sci . 30 : 828 .Montgomery, M.W. y Day, E.A.- "Aldehyde-amine condesation reaction: a possible fate of carbonyls in food".- J. Food Sd. 30 (1965) 828-832....
Agonism of the AhR has recently been identified as a mechanism of myelosuppression by polycyclic hydrocarbons (primarily dioxin and benzene). AhR is a ligand-activated cytoplasmic transcription factor expressed in HSCs that regulates cell cycle entry to prevent premature exhaustion of the quiescent stem...
Keto-aldehyde-amine addition products and method o 优质文献 相似文献 引证文献A Mild and Efficient Palladium-Catalyzed Cyanation of Aryl Mesylates in Water or tBuOH/Water water could be used as the reaction medium without a cosolvent, and a variety of substituents R, such as keto, aldehyde, es...
Aldeyde PEG is an amine reactive PEG derivative that can be used to modify biomolecules via available amine groups. The reaction between aldehyde group with ε-amine of lysine residues and the α-amine at the N-terminus produces an intermediate Schiff base. Further reduction with hydride will fo...
In human breast cancer cells, a complex of β-catenin and NF-κB is formed that reduces transactivation of NF-κB (Deng et al., 2002a). Hence, the activation of NF-κB by protocatechualdehyde is the plausible mechanism for the downregulation of β-catenin which can be supported by the ...
The stereodivergent synthesis of NP25302 from amino acid ester 1b and propargylic alcohol ester 2c. Full size image Discussion The possible reaction mechanism was then investigated. Firstly, two modified chiral aldehyde catalysts 3n and 3o were used to promote the model reaction, and only trace ...
Conserved interactions across the three co-structures that are predicted to contribute to affinity and specificity of the HAA inhibitor class include: a Schiff base interaction between the HAA aldehyde group and the amine group of Lys907; a hydrogen-bond interaction between the HAA hydroxy group ...
The reaction mechanism wasfound to involve two steps, namely: (1) formation of a carbinolamine and (2) dehydration of the carbinolamine to give the finalschiff base, through six-membered ring transition states. The carbinolamine is intermediate and dehydration is rate determiningstep of the ...
ALDH2 also appears to promote the development of coronary collateral vessels in response to chronic ischemia via a mechanism dependent on hypoxia-inducible factor 1 and vascular endothelial growth factor signaling pathways [125]. Interestingly, the effect of heavy alcohol consumption to exacerbate stroke...
The reaction is catalyzed by P450 or MAO enzymes. A key requirement for imine formation is the presence of an oxidizable α-carbon atom adjacent to the amine nitrogen. For amines to be MAO substrates, the most important structural feature is the crucial requirement of two hydrogen atoms on ...