AL amyloidosis: Singapore Myeloma Study Group consensus guidelines on diagnosis, treatment and managementdoi:10.47102/annals-acadmedsg.2023101Melinda TanYunxin ChenMelissa Ooide Mel, SanjayTan, DarylCinnie SoekojoTso, AllisonChun Yuan KhooHui Zhuan Tan...
AL型系统性淀粉样变性的诊治措施 AL型系统性淀粉样变性的诊治措施 梅奥诊所／肾脏病理学会关于肾小球肾炎病理分类、诊断及报告共识 定义 •由于淀粉样纤维（一种细胞外异常折叠蛋白）的聚集引起器官和组织损伤所导致的一类疾病，可以侵犯任何器官 •根据淀粉样纤维前体的不同，共有20余种亚型，其中14种可引起系统性...
Treatment of systemic AL amyloidosis relies mainly on chemotherapy aimed at suppressing the underlying plasma cell clone secreting amyloid-forming Ig LC. AL amyloidosis results from a balance between amyloid deposition and clearance of deposits. The decrease or halting in the production of amyloidogenic...
Treatment of systemic AL amyloidosis relies mainly on chemotherapy aimed at suppressing the underlying plasma cell clone secreting amyloid-forming Ig LC. AL amyloidosis results from a balance between amyloid deposition and clearance of deposits. The decrease or halting in the production of amyloidogenic...
29、e-2-carboxylic acid,Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis. NATURE,CPHPC与SAP,不良反应,无严重不良反应 使用CPHPC可出现一过性头痛、恶心 输入抗SAP抗体200mg时,出现一过性输液反应,12小时后出现轻度头痛、潮红、血压波动、恶心、腹泻等 通过改变...
一、患病率美国一项调查研究结果显示,未校正的AL型心脏淀粉样变(cardiac amyloidosis,AL-CA)的患病率从2007年的15.5例/百万人显著增长至2015年的40.5例/百万人(约为1/25 000),年变化率(annual percentage …
5.Treatment Guidelines:Multiple Myeloma 6.Sanchorawala V, et al.Amyloid . 2022 Mar;29(1):1-7. 7.NCCN Guidelines.Systemic Light Chain Amyloidosis Version 1.2025-September 13,2024. 8.Pinney JHet al.J Clin Oncol. 20...
Treatment of immunoglobulin light chain amyloidosis No therapy is uniformly effective in the management of immunoglobulin light chain amyloidosis (AL amyloidosis). Despite the common generalization, therapy ... MA Gertz,SR Zeldenrust - 《Curr Hematol Malig Rep》 被引量: 171发表: 2009年 Light chain...
Refinement in patient selection to reduce treatment-related mortality from autologous stem cell transplantation in amyloidosis. Bone Marrow Transplant, 2013, 48(4): 557-561. 39 ppt 课件 . 适应征 对年龄≤ 7 0 岁,体能状态评分( E C O G )≤ 2 ,肌钙蛋白 T < 0 . 0 6 n g / m L ,...
In low-risk patients, high doses of melphalan along with autologous stem cell trans plantation (ASCT) is still the treatment of choice [2,6,8]. The monoclonal antibody daratumumab is promising for AL amyloidosis treatment; it is being studied in different trials as both monotherapy and ...