Akkermansia muciniphila是肠道黏液层中主要的黏液蛋白降解菌之一,在哺乳动物中的丰度约为2%-至5%。A. muciniphila可以增加产生黏液的杯状细胞的数量,加速黏液的周转率,对肠道屏障的完整性是有益。A. muciniphila已被证明可以减轻代谢紊乱,如肥胖症、高血压、自闭症和癌症。一些证据报道,A. muciniphila的某些有益...
A. muciniphila, a potential probiotic candidate colonized in the human intestinal mucus layer, and its derivatives have various physiological functions, including treating metabolic disorders and maintaining human health. This review systematically explicates the abundance change rules of A....
Ever since Akkermansia muciniphila was discovered and characterized two decades ago, numerous studies have shown that the lack or decreased abundance of this commensal bacterium was linked with multiple diseases (such as obesity, diabetes, liver steatosi
肠道中低浓度的Akkermansia muciniphila可能表明黏液层较薄,从而导致肠道屏障功能减弱,此外还会增加细菌毒素的易位,炎症性肠病、哮喘、肥胖症和 II 型糖尿病患者的Akkermansia muciniphila浓度往往较低。 我们知道整个胃肠道 (GI) 的粘膜完整性对于维持人体健康至关重要。这其中,粘液屏障的完整性是胃肠道的第一道防线。
A Korean study led by Seoul National University scientists is the first to demonstrate that the human intestinal mucin-degrading bacterium,Akkermansia muciniphila, secretes a glucagon-like peptide-1 (GLP-1)-inducing protein, which significantly improved glucose homeostasis and ameliorated metabolic disease...
Akkermansia muciniphila(A. muciniphila)is another member of humangut microbiota, whose population is significantly reduced inmetabolic disorderssuch astype 2 diabetes. There are evidence that not only these bacteria and specifically theirOMVshave immunomodulatory effect, but also they are essential for ...
嗜黏蛋白阿克曼菌Akkermansia muciniphila 价格￥3000 起批量≥1瓶 最小起订1瓶 供货总量20瓶 发货地址上海市奉贤区 建议售价￥3000/瓶 更新日期2025年02月07日 产品规格冻干粉;菌液;平板 即时洽谈立即询价查看联系方式 收藏产品发送留言 VIP3年 上海科博瑞生物科技有限公司 ...
This study indicated that some PCa patients and mice were more sensitive to ADT and entered CRPC later, which was related to the gut microbiota, especially the enrichment of Akkermansia muciniphila (AKK). Untargeted metabolomics analysis found that serum inosine level was upregulated in the ...
The gut bacterium Akkermansia muciniphila has been increasingly recognized for its therapeutic potential in treating metabolic disorders, including obesity, diabetes, and metabolicdysfunction-associated fatty liver disease (MAFLD). However, its underlying mechanism involved in its well-known metabolic actions...
嗜粘蛋白-阿克曼氏菌(Akkermansia muciniphila,A.muciniphila),简称为AKK,于 2004 年发现,是一种从人类粪便中分离出来的椭圆形革兰氏阴性细菌。 该细菌以荷兰微生物生态学家Anton DL Akkermans 的名字命名,以表彰他对该领域的贡献。A. muciniphila 是人类肠道共生菌,并可以依靠肠粘液层的黏蛋白生存。