2012年全球肾脏疾病预后改善组织( Kidney Disease Improving Global Outcomes,KDIGO)将既往RIFLE(Risk,Injury,Failure,Loss,End-Stage Renal Disease)标准和AKIN( Acute Kidney Injury Network)标准结合起来推出统一的AKI诊断标准,以提高AKI诊断的敏感性,但KDIGO对于AKI的定义依据的仍然是功能标志物异常(血肌酐升高或少尿)...
A retrospective cohort study has revealed an association between recovery of kidney function after an episode of acute kidney injury (AKI) in patients with normal baseline kidney function and increased risk of incident chronic kidney disease (CKD) stage 3. Over a median follow-up of 2.5 years, ...
including the immune system response and cell metabolic reprogramming in the kidney. Continuous and severe stimulation can lead to cell death, organ failure, and end-stage renal disease (ESRD). Moreover, different responses to cell repair determine different prognoses. Some cells are ...
Renal ischemia/reperfusion (I/R) was used to induce a mouse model of AKI-CKD transition. We used verteporfin (VP), a pharmacological inhibitor of YAP, to treat post-IRI mice for a period, and evaluated the influence of YAP inhibition on long-term outcomes of AKI. In our results, severe...
Long-term risk of mortality and end-stage renal disease among the elderly after small increases in serum creatinine level during hospitalization for acute myocardial infarction. Arch Intern Med. 2008;168:609–16. Article CAS PubMed Google Scholar Thakar CV, Christianson A, Freyberg R, Almenoff ...
Intravenous Contrast is Associated with AKI in Patients with Stage 1–3 CKD: PROdoi:10.34067/KID.0000000000000186clinical nephrologyAKICKDTariku Tadele GuduraDepartment of Kidney Medicine, Cleveland Clinic, Cleveland, OhioMohamed HassaneinDepartment of Nephrology and Hypertension, University of Mississippi ...
Intravenous Contrast is Associated with AKI in Patients with Stage 1–3 CKD: Commentarydoi:10.34067/KID.0000000000000403AKICKDintravenousDinna N. CruzDivision of Nephrology-Hypertension, University of California, San Diego, San Diego, California
Despite research on the role and cellular mechanism of autophagy in AKI, the role of autophagy in the progression to chronic kidney disease (CKD) remains poorly understood. Here, using farnesoid X receptor (FXR) knockout (KO) mice, we determined whether FXR prevents the progression of AKI to...
Intravenous contrast is associated with AKI in patients with stage 1-3 CKD: CON.AKI and ICU nephrologyAKICKDcontrastrenalismdoi:10.34067/KID.0000000000000187J. TurnerAmerican Society of NephrologyKidney360
The overall preoperative incidence of chronic kidney disease (CKD) in this study population was 17.19%, out of which 68.18% was KDIGO 3a stage, and the remaining 31.82% was KDIGO 3b stage. In the AKI group, there was a higher percentage of patients who underwent complex procedures (coronary...