M1 临床有转移征象,并且组织学证实转移灶大于0.2mm; Rapid advances in both clinical and laboratory science and in translational research have raised questions about the ongoing relevance of TNM staging, especially in breast cancer. The TNM system was developed in 1959 in the absence of effective syste...
000 patients from 10 centers worldwide with stages I, II, and III melanoma diagnosed since 1998. Based on analyses of this new database, the existing seventh edition AJCC stage IV database, and contemporary clinical
integration of AJCC stage with ATA risk moves from a “one size fits all” prognostic approach to a more refined and individualized DSS estimate than AJCC stage alone. From a practical standpoint, we integrate AJCC stage...
undergo initial radical surgery), the prognostic performance of both 7 th and 8 th stages for both overall survival and pancreatic cancer-specific survival was limited.Conclusion: There is clearly a need to have two staging systems for pancreatic adenocarcinoma: pathological and clinical staging ...
early-stage breast cancers and total mastectomy with axillary dissection for more advanced disease; (2) reduction in the extent of axillary staging, with sentinel lymph node biopsy becoming the leading approach for patients with clinically negative axillae; (3) ...
Stage group According to the 8th AJCC clinical stage, the 5-year OS rates of the enrolled patients with stages II, III, IVa and IVb (with metastatic SLNM) were 62.0, 24.5, 35.8 and 25.1%, respectively. The survival of those with stage II was higher compared to stages III, IVa and IVb...
(T1a,<0.8 mm without ulceration; T1b, 0.8-1.0 mm with or without ulceration or <0.8 mm with ulceration), with mitotic rate no longer a T category criterion; 3) pathological (but not clinical) stage IA is revised to include T1b N0 M0 (formerly pathologic stage IB); 4) the N ...
AJCC 8th edition prognostic staging was a better predictor of OS than 7th edition anatomic staging for both clinical stage [area under the curve (AUC) 0.67 vs. 0.62, p < 0.01] and pathological stage (AUC 0.70 vs. 0.66, p < 0.01). Conclusions Sixty-five percent of patients have a shift...
杂合性缺失）对II期结肠癌预后影响 TNM分期几个概念 •临床分期Clinicalstage(pretreatmentstage)手术、新辅助治疗及其他治疗前的分期cT/cN/cM作用：判断预后、决定初始治疗、人群比较 •病理分期Pathologicstage 通过手术以及术后切除标本的组织学进行分期
AJCC 第8 版乳腺癌分期系统针对解剖学分期(anatomic stage group)和预后分期(prognostic stage group)标准;原发肿瘤(T)、区域淋巴结(N)、远隔部位转移(M)的定义;以及生物学标记物和多基因检测的临床意义等内容作出修订(表1)。 2 AJCC 第8 ...