Taken together, montelukast treatment reduced microglia activation, elevated neurogenesis, and restored cognitive function in old rats. Regression and correlation analyses showed that learning did not correlate with microglial soma size (R2=0.001) and that the montelukast-induced learning improvement was ind...
Keywords: spatial accessibility; aging services; residential aged care facilities (RACFs); Wuhan 1. Introduction In 1982, the Vienna World Assembly on Aging acknowledged that when the senior population proportion (aged 65 and above) is more than 7%, the country or region would enter a seriously...
(3 cycles of 15 s) and clarified with a centrifugation of 16,000×gat 4 °C for 10 min. Protein quantification was determined by Bradford assay with Bio-Rad DC reagent (Sigma-Aldrich, St. Louis, MO, USA). All samples were prepared with the same amount of total protein (70 µg),...
Viability of magnetically captured cells (eluted into a new tube away from the magnet) was assessed by trypan blue staining (1:2 dilution sample in trypan blue; Cat#1450013; Bio Rad, Hercules, CA USA). Cell viability was quantified as the proportion of cells that did not take up the ...