HRmax was univariately explained by the formula 211 − 0.64·age (SEE, 10.8), and we found no evidence of interaction with gender, physical activity, VO2max level, or BMI groups. There were only minor age-adjusted differences in HRmax between these groups. Previously suggested prediction...
HRmax was univariately explained by the formula 211-0.64路age (SEE, 10.8), and we found no evidence of interaction with gender, physical activity, VO2max level, or BMI groups. There were only minor age-adjusted differences in HRmax between these groups. Previously suggested prediction equations...
1). Using a generalized additive model (GAM) approach, we found that all 51 phenotypes showed nonlinear age-dependent sex differences (Supplementary Table 4), and 16 of the 51 phenotypes (31%) showed a significant age by sex interaction with a considerable effect size (Bonferroni-adjusted ...
and vegetable intakes across all clocks (Additional file1: Table S1), except for vegetable-adjusted intake that was inversely correlated with the PCGrimAge (r = − 0.141,p = 0.024). Meat intake was not correlated with either age or any of the mAge signatures (i.e., mAge...
clock (clock 1), regresses log-transformed chronological age on DNA methylation levels of all available mammals. Although such a clock can directly estimate the age of any mammal, its usefulness could be further increased if its output were adjusted for differences in the maximum lifespan of each...
1) What -if any- among the many conclusions of your abstract do you think should be adjusted/modulated to the around 20 years of time elapswd and science produced? 2) The abstract states that, “without predation, aging gives no advantage”. But why so? And, could you perhapa eelate ...
Since the first BPD measurement failed to recognize the small growth pattern and, therefore, underestimated gestational age, the second measurement allows the gestational age assessment to be adjusted based on the BPD growth pattern. Such a fetus with a slowed growth pattern would have the ...
In model 2, physical activity was further adjusted. Likelihood ratio tests were used to detect the interaction between different age groups. To illustrate the different associations between TGI and mortality in middle-aged patients and old patients, Kaplan–Meier estimate curves and restricted cubic ...
b The association between methylation drift rate and lifespan. The x axis represents maximum longevity of each species (mouse; 4 years, monkey; 40 years, human; 122.5 years), and the y axis represents methylation changes per year. The scales are logarithmic. The maximum longevities of the ...
4, Fig. 5. Overlapping, age-adjusted windows of 10% of observations are plotted, with age on the x-axis corresponding to the median age of participants within the overlapping quantile windows. Because there are fewer observations within particularly young (starting at 45 years) and ...