Evidence for the direct involvement of RNA in the initiation of DNA replication in Escherichia coli 15T− The chromosomes of Escherichia coli 15T− and a streptolydigin-sensitive mutant, 15T− lyd-4, were aligned by amino-acid starvation and labeled at thei... Karl,G.,Lark - 《...
In these cases replication time is also prolonged after each doubling. Duration of DNA synthesis increases linearly but always by a smaller factor as the corresponding DNA content is increased. 展开 DOI: 10.1007/BF00300391 被引量: 19 年份: 1976 ...
( 1993 ) Determination of initiation of DNA replication before and after nuclear formation in Xenopus egg cell free extracts . J. Cell Biol. 123 , 1321 – 1331 .Kubota, Y. & Takisawa, H. ( 1993 ) Determination of initiation of DNA replication before and after nuclear formation in Xenopus...
Why is chromatin packaged after DNA replication? Principles of Chromosomal Organization: Outside of cell division, the genetic material of eukaryotic cells in higher organisms is compartmentalized into a nucleus. The DNA strands of each chromosome are wrapped around specialized scaffolding proteins to for...
Normal replication of DNA after repair replication in bacteria. Nature. 1967; 214 (5085):269.Hanawalt, P.C. 1967. Normal replication of DNA after repair replication in bacteria. Nature 214(5085), 269.P.C. Hanawalt, Normal replication of DNA after repair replication in bacteria, Nature 214...
In spite of its highly condensed state, sperm DNA is vulnerable to damage that can originate from oxidative stress, the activity of sperm-specific nucleases, or both. After fertilization, in the oocyte, paternal chromatin undergoes dramatic changes, and during this extensive remodeling, it can be...
Figure 7. Transcription Re-establishes the Accessible Chromatin Landscape Post- DNA Replication( DNA复制后转录重建染色质开放区域 ) 涉及分析方法以及数据结果 1、主要分析方法 ·实验模型和主题细节 ··mESC Cell Culture ··Drosophila S2 Cell Culture ...
DNA replicationchromatin assemblyRNA polymeraseATAC-seqactive chromatinrepli-ATAC-seqDNA replication is highly disruptive to chromatin, leading to eviction of nucleosomes, RNA polymerase, and regulatory factors. When and how transcription resumes on DNA following DNA replication is unknown. Here we ...
Homologous recombination (HR) plays critical roles in repairing lesions that arise during DNA replication and is thus essential for viability. RAD51 plays important roles during replication and HR, however, how RAD51 is regulated downstream of nucleofilament formation and how the varied RAD51 function...
Children conceived through assisted reproductive technologies (ART) have an elevated risk of lower birthweight, yet the underlying cause remains unclear. Our study explores mitochondrial DNA (mtDNA) variants as contributors to birthweight differences by