The affinity of hemoglobin for oxygen affects ventilatory responses in mutant mice with Presbyterian hemoglobinopathy. Am J Physiol Regul Integr Comp Physiol 285: R747-R753, 2003.Izumizaki M, Tamaki M, Suzuki Y, Iwase M, Shirasawa T, Kimura H, Homma I. The affinity of hemoglobin for oxygen...
Increases in the affinity of hemoglobin for oxygen (Hb-O2 affinity) may also produce tissue hypoxia and such Hb-O2 affinity changes have been implicated in the pathogenesis of diabetic microangiopathy. In order to test whether affinity hypoxia might contribute to the development of diabetic ...
During a sickle cell crisis, deoxygenated sickle hemoglobin (deoxyHbS) polymerizes to form fibers in red blood cells (RBCs), causing the cells to adopt “sickled” shapes. Using small molecules to increase the affinity of Hb for oxygen is a potential approach to treating sickle cell disease, ...
(19666). The effect of hemolysis upon the oxygen affinity of hemoglobin in the Atlantic (Salmo salar) and landlocked salmon (Salmo salar sebago), Jf. Fish. Res. Bd Can. 23, 1575-80.BLACK, E. C.; TUCKER, H. H.; KIRKPATRICK, D. The effect of hemolysis upon the oxigen affinity of ...
As a typical compensatory reaction one might expect changes in oxygen affinity of hemoglobin. Therefore position (standard half saturation pressure P50st) and slope (Hill's n) of the O2 dissociation curve as well as the Bohr coefficients (BC) for CO2 and lactic acid were determined in blood ...
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of Ped., Coll. of Physicians and Surgeons, globin molecular structure can produce rapid and Columbia Univ., New York (introduced by profound changes in the organization of hemoglobin John C.Sinclair). into gels or crystals. The effect of DPG on the affinity of hemoglobin for oxygen, expressed...
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Relative Affinity M Constant of Adult and Fetal Hemoglobin for Carbon Monoxide in Humans: a Systematic Review and Meta-Analysis The Haldane M constant represents the ratio of oxygen/carbon monoxide affinity to hemoglobin. Findings on M values appear to be quite variable among studie... N Delvau...
of Ped., Coll. of Physicians and Surgeons, globin molecular structure can produce rapid and Columbia Univ., New York (introduced by profound changes in the organization of hemoglobin John C.Sinclair). into gels or crystals. The effect of DPG on the affinity of hemoglobin for oxygen, expressed...