Adverse effects of androgen deprivation therapy in men with prostate cancer: a focus on metabolic and cardiovascular complications. Asian J Androl. 2012;14(2):222-225.Collins L & Basaria S 2012 Adverse effects of androgen deprivation therapy in men with prostate cancer: a focus on metabolic ...
With the increasing indications for the use of androgen-deprivation therapy in the treatment of men with prostate cancer, side effects of the therapy deser... JM Holzbeierlein,EP Castle,JB Thrasher - 《Clinical Genitourinary Cancer》 被引量: 184发表: 2008年 Adverse effects of androgen deprivatio...
Androgen deprivation therapy (ADT) induces severe hypogonadism and is associated with several adverse effects that negatively affect health and quality of life in patients with prostate cancer. ADT changes body composition characterized by an increase in fat mass and a reduction in muscle mass and str...
New hormonal compounds such as selective androgen receptor modulators capable of specifically targeting prostate cancer are expected to be developed. 展开 关键词: adverse effects androgen deprivation therapy hormonal therapy prostate cancer DOI: 10.1038/aja.2011.121 被引量: 15 ...
Prostate cancer (PCa) patients initiating androgen deprivation therapy (ADT) are suffering from adverse effects; exercise has been proposed as a treatment to relieve adverse effects of ADT, available meta-analysis has proved exercise improves quality of life, and therapy caused fatigue; recently, some...
Patients with non–small cell lung cancer who had mild/moderate immune-related adverse effects appear to have improved overall survival compared with those without following atezolizumab-based therapy. Evaluating Treatment Options and the Multidisciplinary Care of Ocular Toxicities of MEK Inhibitors David ...
Adverse Effects Adverse effects of danazol that reflect inhibition of the pituitary-ovarian axis include menstrual disturbances and amenorrhoea (occasionally persistent), hot flushes, sweating, reduction in breast size, changes in libido, vaginal dryness and irritation, emotional lability, and ...
glucocorticoids but in women therapy with aromatase inhibitors, fractural osteoporosis is also identified, Type 2 diabetes mellitus treatment for men and women who are treated with antiandrogen therapy in prostate cancer and women treated with elevated amounts of thyroxine following menopausal procedures....
discontinuation of multi-kinase inhibitor (MKIs), imatinib therapy due to TKI-associated adverse effects.10Toxicity can be attributed to bothon-targeteffects through excessive inhibition of the intended TK function; and/oroff-targeteffects resulting from the simultaneous inhibition of multiple other ...
Effects of ADT on bone mass, structure and strength. aBMD, areal bone mineral density; ADT, androgen deprivation therapy; vBMD, volumetric bone mineral density. Changes to bone health and body composition associated with androgen deprivation therapy Bone mineral density, structure and strength. It ...