Adverse Effects Gastrointestinal disturbances are the most frequently reported adverse effect after the oral use of ketocona- zole. Nausea and vomiting have been reported in about 3% of patients, and abdominal pain in about 1%. These adverse effects are dose-related and may be minimised by ...
The study concludes a temporal coincidence of vaccination and stroke but highlights that a cause–effect relationship is only hypothetical. Indeed, three of the 12 patients were also on hormone therapy/contraceptives, which could provide an alternative explanation for PFO-associated stroke. To our ...
The reduced effect of carbamazepine on THP-1 cells might be explained by the absence of metabolizing enzymes necessary for carbamazepine pre-activation, as occurred with sulfamethoxazole (Sanderson et al., 2007; Elsheikh et al., 2010). Nevertheless, in other studies, carbamazepine pre-activation ...
Asthma and chronic obstructive pulmonary disease (COPD) are common disorders that are associated with increasing morbidity and mortality in older people. Bronchodilators are used widely in patients with these conditions, but even when used in inhaled form can have systemic as well as local effects. ...
Blum RA, D’Andrea DT, Florentino BM. Increased gastric pH and the bioavailability of fluconazole and ketoconazole. Annals of Internal Medicine 114: 755–757, 1991a PubMedCASGoogle Scholar Blum RA, Wilton JH, Hilligoss DM. Effect of fluconazole on the disposition of phenytoin. Clinical Pharmacolo...
Cyclosporin is a potent, widely used specific immunosuppressive agent which affects T-helper cells, and has little myelotoxicity. Its pharmacokinetics are
[45] elucidated this hypothesis by studying the effect of different proportions of β-CN variants on milk, monitoring consumption by individuals with health conditions associated with comorbidities. Symptoms associated with gastrointestinal discomfort were correlated with the consumption of A2A2 milk, milk...
Background: Patients with end-stage renal disease (ESRD) require specialized therapeutic interventions. The decreased renal function that modulates the physiology and presence of comorbidities is often associated with variations in the pharmacological re
Until about 2020, it was generally thought that the associations between PD and such outcomes might be caused by systemic inflammation or by the effect of periodontopathic bacteria. However, it is now realized that the associations are not causal but due largely to shared risk factors such as ...
2. Clothing and Its Effect on Thermoregulation The skin performs multiple metabolic functions related to thermoregulation, sensorial perception, and protection. This organ is made up of the epidermis, dermis, and hypo- dermis. The dermis contains the so-called annexes; that is, hair follicles and...