vesicles.Nanocarriers can overcome a variety of key biological barriers,improve drug bioavailability,increase intracellular penetration and retention time,achieve drug enricXingshuang SongSchool of Pharmaceutical Sciences University of Traditional Chinese Medicine ProvinceYizhi ZhangDepartment...
Nanocarriers are known to exploit the enhanced permeability and retention (EPR) effect for targeting to tumors thereby increasing tumor drug concentrations while minimizing systemic toxicity. According to the different materials and structures, these carriers can be divided into lipid NPs, polymeric NPs,...
Recent progress of targeted nanocarriers in diagnostic, therapeutic, and theranostic applications in colorectal cancer Biomater. Adv., 153 (2023), Article 213556 View PDFView articleView in ScopusGoogle Scholar [3] Y. Wang, Y. Cong, M. Cai, X. Liang, L. Wang, D. Zhou Charge-conversional ...
Among different novel drug delivery systems, phytosomes are well-known as biocompatible nanocarriers that have been used to improve solubility and permeability of different phytopharmaceuticals. They are considered as self-assembled nanocarriers that based on phospholipid complexation approach. This type of ...
was observed. Thein vitroCUR release from NLC was slower than that of CUR-NLC and chitosan hydrochlorides (CH) coated NLC due to the inter and/or intramolecular disulfide formation of thiomers on the surface of nanocarriers. The modification also significantly enhanced transcorneal penetration ...
aThe current review highlights the main advances achieved in utilizing protein nanocarriers as natural vehicles for drug and gene delivery tasks with respect to types,advantages, limitations, formulation aspects as well as the major outcomes of the in vitro and in vivo investigations. 当前回顾突出在...
in vaccine development. However, the unique biopharmaceutical hurdles that intranasally or orally delivered protein vaccines need to overcome before they reach the sites of targeting, the relatively low immunogenicity, as well as the low stability of the protein antigens, require thoughtful and fine-...
(2)Contrast in detail the different means to load drugs and the selection of drug loading means;(3)Discuss multiple ferritin functionalization approaches,together with related advantages and potential risks;and,(4)Compare ferritin with alternative,commonly-used drug nanocarriers.We conclude that despite...
The advantages of wide availability, high yield, brain tumor-homing ability, inhibition of tumor growth and suppression of angiogenesis make MSCs-derived EVs as superior natural nanocarriers to treat GBM (Liu et al., 2024a, Yuan et al., 2017, Zhang et al., 2020). Secondly, tumor cell-...
nanocarrier; (2) Contrast in detail the different means to load drugs and the selection of drug loading means; (3) Discuss multiple ferritin functionalization approaches, together with related advantages and potential risks; and, (4) Compare ferritin with alternative, commonly-used drug nanocarriers....