Age effects on the regulation of adult hippocampal neurogenesis by physical activity and environmental enrichment in the APP23 mouse model of Alzheimer disease. Hippocampus. 2009;19:1008–18. CAS PubMed Google Scholar Hoglinger GU, Rizk P, Muriel MP, Duyckaerts C, Oertel WH, Caille I, et ...
We developed a new screening platform utilizing primary adult mouse cortical neurons and demonstrated sex- and age-dependent effects of neuroactive compounds. This discrepancy between demographics supports the notion that future screenings must include both sexes and different age groups to account for se...
Previous reports have suggested various SGA mouse models through dietary restriction of pregnant dams, but their low reproducibility is no small limitation. Therefore, we attempted to improve SGA mouse models with high reproducibility by modifying the dietary restriction. We ...
Hertzum, M., Hornbaek, K.: How age affects pointing with mouse and touchpad: A comparison of young, adult, and elderly users. Int. J. of HCI 26(7), 703-734 (2010)Hertzum, M. & Hornbaek, K. (2010). How age affects pointing with mouse and touchpad: A comparison of young, ...
An organ culture system by which adult mouse colon epithelium could be maintained in a modified form for several weeks was described. The effects of donor age and carcinogen pretreatment were studied as a preliminary to proposed experiments on the effect of carcinogen treatment in vitro on colon ...
We examined the effects of sex and age on parental motivation in the California mouse, a monogamous, biparental rodent. We compared parental motivation of male and female virgins in both mid- and old adulthood using two new tests – a T-maze test and a rain test – as well as in ...
Ovariectomy has no effect on the fiber type composition in females. We conclude that testosterone plays a role in the maintenance of MHC expression in the adult male mouse masseter. 展开 关键词: Animals Mice, Inbred C57BL Mice Ovariectomy Blotting, Western Age Factors Antibody Specificity ...
The results suggest that administration of melatonin at birth may interfere with the differentiating gonadal and adrenal central nervous system control centers during the critical neonatal period in the mouse and rat.(AUTHORS MODIFIED) 展开 关键词: Laboratory Animals Ovarian Effects Adrenal Cortex Effects...
(Supplementary Fig.1a–d), but not in the adult mouse cochlea (Supplementary Fig.1f). The cochleostomy procedure in adults damages a majority of the outer hair cells (OHCs) around the injection site, consistent with our previous study28. To study the independent effect ofNotch1activation, ...
(Fig.4c). In the EPDCs, we foundSEMA3D, involved in concerted endothelial cell migration36;CCBE1, important in mouse cardiac development37;EGFL6, associated with angiogenesis38, andGPC3, reported to modulate WNT signaling39. Overall, these results suggested further that these epicardial cells are...