In a Canadian study that examined patients with prostate cancer who had a rising PSA or were PSA recurrent, intermittent androgen deprivation therapy (ADT) was found to be noninferior to the continuous dosing strategy, suggests David I. Quinn, MD.For this small subset of patients, an intermitte...
Impact on overall survival (OS) with chemohormonal therapy versus hormonal therapy for hormone-sensitive newly metastatic prostate cancer (mPrCa): An ECOG-led phase III randomized trial.(Abstract #LBA2) Background: Docetaxel (D) improves OS of men with mPrCa who have progressed on androgen depr...
Androgen deprivation therapy (ADT) is the main treatment for advanced prostate cancer and is increasingly used in combination with radiotherapy in patients with earlier stages of prostate cancer. For many years, gonadotropin-releasing hormone (GnRH) agonists have been the ADT standard of treatment. ...
[7] Efstathiou E, et al. Clinical and Biological Characterisation of Localised High-risk Prostate Cancer: Results of a Randomised Preoperative Study of a Luteinising Hormone-releasing Hormone Agonist with or Without Abiraterone...
Dr. Simon J. Crabb:At ASCO 2024, we presented data from the MANCAN2 study, a randomized trial where prostate cancer patients on ADT with hot flushes were assigned to receive either standard care or CBT. We found tha...
Androgen deprivation therapy (ADT) in men with prostate cancer (PCa) results in adverse effects, including reduced muscle strength and physical function, potentially compromising daily functioning. We examined whether it was more efficacious to commence exercise at the onset of ADT rather than later ...
Dr. Simon J. Crabb:At ASCO 2024, we presented data from the MANCAN2 study, a randomized trial where prostate cancer patients on ADT with hot flushes were assigned to receive either standard care or CBT. We found that CBT significantly reduced the impact of hot flushes at early time points...
N Sharifi,JL Gulley,WL Dahut - Endocrine-related cancer 被引量: 345发表: 2010年 Lifestyle intervention in men with advanced prostate cancer receiving androgen suppression therapy: a feasibility study. This preliminary evidence suggests that pragmatic lifestyle interventions have potential to evoke impro...
It is not known whether short-term androgen-deprivation therapy (ADT) before and during radiotherapy improves cancer control and overall survival among patients with early, localized prostate adenocarcinoma.From 1994 through 2001, we randomly assigned 1979 eligible patients with stage T1b, T1c, T2a, ...
progression of high-risk localized prostate cancer in US veterans, who are disproportionately impacted by the disease compared to the general population. The research will begin by analyzing data from over 5,000 veterans who have been diagnosed with high-risk prostate cancer and...