原文来源: Li JR, Wang SS, Chen CS, Cheng CL, Hung SC, Lin CH, Chiu KY. Conventional androgen deprivation therapy is associated with an increased risk of cardiovascular disease in advanced prostate cancer, a nationwide popul...
参考文献 [1] Sarah Blanchet-Deverly, et al. Long survivors after androgen deprivation therapy (ADT) with or without docetaxel for metastatic castration-sensitive prostate cancer (mCSPC): Long-term follow-up of GETUG-15. E...
1941年,Huggins和Hodges发现手术切除双侧睾丸可延缓转移性前列腺癌的进展,首次证实了前列腺癌对去除雄激素的反应性,奠定了前列腺癌雄激素剥夺治疗(Androgen deprivation therapy,ADT)的基础。无论是国外NCCN、AUA、EAU指南,还是国内CUA指南,均推荐ADT是激素敏感性前列腺癌(CSPC)和去势抵抗性前列腺癌(CRPC)最主要的标准治疗...
[2]Casado E, Borque-Fernando A, Caamaño M, et al. Multidisciplinary Consensus on the Prevention and Treatment of Osteoporosis and Fragility Fractures in Patients with Prostate Cancer Receiving Androgen-Deprivation Therapy. The World Journal of Men's Health, 2022, 40(1): 74. [3]Gómez-Aparic...
[1] 2022 ESMO- LBA9 - Duration of androgen deprivation therapy (ADT) with post-operative radiotherapy (RT) for prostate cancer: First results of the RADICALS-HD trial (ISRCTN40814031). [2] Mottet, N., et al. EAU-EANM-ESTRO-ESUR-ISUP-SIOG Guidelines on Prostate Cancer. Arnhem: European...
[2]Casado E, Borque-Fernando A, Caamaño M, et al. Multidisciplinary Consensus on the Prevention and Treatment of Osteoporosis and Fragility Fractures in Patients with Prostate Cancer Receiving Androgen-Deprivation Therapy. The World Journal of Men's Health, 2022, 40(1): 74. ...
Prostate CancerSudden Cardiac DeathClinical OncologyFragility FractureThe article discusses research on the impact of androgen deprivation therapy (ADT) on diabetes and cardiovascular disease in men with prostate cancer. Results revealed that 1,392 ADT users compared with 1,181 nonusers developed incident...
[2]Ross RW, Xie W, Regan MM, et al. Efficacy of androgen deprivation therapy (Adt) in patients with advanced prostate cancer: Association between Gleason score, prostate-specific antigen level, and prior ADT exposure with duration of ADT effect. Cancer. 2008;112(6):1247-1253. ...
[1] 2022 ESMO- LBA9 - Duration of androgen deprivation therapy (ADT) with post-operative radiotherapy (RT) for prostate cancer: First results of the RADICALS-HD trial (ISRCTN40814031). [2] Mottet, N., et al. EAU-EANM-ESTRO-ESUR-ISUP-SIOG Guidelines on Prostate Cancer. Arnhem: European...
雄激素剥夺疗法(androgen deprivation therapy,ADT)是目前无法行手术的前列腺癌患者的有效治疗方案。 该策略在治疗早期对于大多数患者均有效,但治疗12-18月后,很多患者出现耐药现象,即去势抵抗性前列腺癌(castration resistant prostate cancer,CRPC)。 临床数据 ...